IL-12 R beta 1

IL-12 R beta 1 분자 정보

영어 이름Interleukin-12 receptor시판 약물 수0
임상 약물 수9표적 별명Receptors, Interleukin-12
최고 연구 개발 단계Phase 2 Clinical
영어 이름Interleukin-12 receptor
표적 별명Receptors, Interleukin-12
시판 약물 수0
임상 약물 수9
최고 연구 개발 단계Phase 2 Clinical

IL-12 R beta 1 제품 목록

  • 속성

    Protein (7)

  • 제품 라이브러리

    온라인 (7)

  • Human (4)Cynomolgus (2)Mouse (1)

  • 태그

    His Tag (1)Fc Tag & Avi Tag (1)Fc Tag (2)His Tag & Avi Tag (3)

  • 마커

    Unconjugated (3)Biotin-labeled (4)

IL-12 R beta 1분자 배경

The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

IL-12 R beta 1분자 별명

IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
KLT-1101KLT-1101Phase 2 ClinicalKang Litai Pharmaceutical Co LtdLeukopenia; Melanoma; Sarcoma, Kaposi; Solid tumours; Thrombocytopenia
상세
Edodekin alfaRO 247472; YM 01CPhase 2 ClinicalF. Hoffmann-La Roche Ltd, Valeant, Wistar InstituteAbdominal Neoplasms; Asthma; Bacterial Infections; Breast Neoplasms; Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Graft vs Host Disease; Hepatitis B; Hepatitis C; HIV Infections; Leishmaniasis; Lymphoma; Lymphoma, Non-Hodgkin; Lymphoma, T-Cell, Cutaneous; Malaria; Melanoma; Neoplasms; Sarcoma, Kaposi; Solid tumours; Squamous Cell Carcinoma of Head and Neck
상세
RTX-224RTX-224Phase 2 ClinicalRubius Therapeutics IncCarcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms
상세
KB-707KB707; KB-707Phase 2 ClinicalKrystal Biotech IncCarcinoma, Non-Small-Cell Lung; Lung Neoplasms; Melanoma; Neoplasms; Skin Melanoma; Solid tumours
상세
ASP-9801ASP-9801Phase 1 ClinicalAstellas Pharma IncNeoplasm Metastasis; Neoplasms; Solid tumours
상세
Tolododekin AlfaANK101; ANK-101Phase 1 ClinicalAnkyra Therapeutics IncCarcinoma, Basosquamous; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Rejection of renal transplantation; Skin Neoplasms; Soft Tissue Injuries; Solid tumours
상세
CLN-617CLN-617Phase 1 ClinicalCullinan Therapeutics IncSolid tumours
상세
SON-1010SON-1010Phase 1 ClinicalSonnet Biotherapeutics IncCarcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Sarcoma; Solid tumours
상세
phIL12 GETPhase 1 ClinicalInstitute Of Oncology LjubljanaCarcinoma, Basal Cell
상세

제품 리뷰

  • K***n2024-10-05
    0사람들이 좋아합니다
    I’ve been using the IL12 receptor protein from Acro Biosystem in my antibody discovery research, and I’m highly satisfied with its quality. The protein exhibits excellent stability and bioactivity, which has been crucial in my experiments targeting immune responses. It’s been a reliable reagent, showing consistent results across various assays. I highly recommend this product for anyone involved in immunological research, particularly in therapeutic antibody development.
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  • 제품 목록
  • 제품 리뷰
  • 임상 약물 정보
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