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홈 페이지모든 분자IL-11 R alpha
IL-11 R alpha
IL-11 R alpha 분자 정보
| 영어 이름 | Interleukin 11 receptor alpha | 시판 약물 수 | 9 |
| 임상 약물 수 | 3 | 표적 별명 | Interleukin-11 Receptor Alpha Chain，Interleukin 11 Receptor Subunit Alpha，Interleukin 11 Receptor， Alpha，IL-11R-Alpha，IL-11 Receptor Subunit Alpha，Interleukin-11 Receptor Subunit Alpha，IL11RA，IL-11RA，IL-11R Subunit Alpha，CRSDA，Interleukin-11 Receptor alpha Subunit，sIL-11RA，sIL-11R，sIL11RA |
| 최고 연구 개발 단계 | Approved | ||
| 영어 이름 | Interleukin 11 receptor alpha |
| 표적 별명 | Interleukin-11 Receptor Alpha Chain，Interleukin 11 Receptor Subunit Alpha，Interleukin 11 Receptor， Alpha，IL-11R-Alpha，IL-11 Receptor Subunit Alpha，Interleukin-11 Receptor Subunit Alpha，IL11RA，IL-11RA，IL-11R Subunit Alpha，CRSDA，Interleukin-11 Receptor alpha Subunit，sIL-11RA，sIL-11R，sIL11RA |
| 시판 약물 수 | 9 |
| 임상 약물 수 | 3 |
| 최고 연구 개발 단계 | Approved |
IL-11 R alpha 제품 목록
- 속성
Protein (6)Cell (1)
- 제품 라이브러리
온라인 (7)
- 종
Human (4)Mouse (2)Rhesus macaque (1)
- 태그
Fc Tag (1)Fc Tag & Avi Tag (1)His Tag (2)- (1)Avi Tag (1)His Tag & Avi Tag (1)
- 마커
Unconjugated (3)Biotin-labeled (3)- (1)
| 제품 번호 | 종 | 발현 시스템 | 제품 설명 | 단백질 구조 | 순도 | 특성 |
|---|---|---|---|---|---|---|
HOT CHEK-ATF052 |  Human | HEK293 | Human IL-11 R alpha (Luc) HEK293 Reporter Cell |  | ||
HOT ILR-H5256 | Human | HEK293 | Human IL-11 R alpha Protein, Fc Tag (MALS verified) |  |  |  |
HOT ILR-H52H5 | Human | HEK293 | Human IL-11 R alpha Protein, His Tag, low endotoxin (MALS & BLI verified) |  | | |
HOT ILR-H82F5 | Human | HEK293 | Biotinylated Human IL-11 R alpha Protein, Fc,Avitag™ (MALS verified) |  | | |
HOT ILR-M52H9 |  Mouse | HEK293 | Mouse IL-11 R alpha Protein, His Tag |  | | |
| Mouse | HEK293 | Biotinylated Mouse IL-11 R alpha Protein, Avitag™ |  | | | |
 Rhesus macaque | HEK293 | Biotinylated Rhesus macaque IL-11 R alpha Protein, His,Avitag™ (MALS verified) |  | | |
총 수량7
- 1
IL-11 R alpha분자 배경
Interleukin-11 receptor subunit alpha (IL-11RA) is a type I transmembrane hematopoietic cytokine receptor serving as the ligand-specific binding subunit for IL-11. It harbors an extracellular cytokine-binding homology region, binds IL-11 with low affinity on its own, and recruits the shared, ubiquitously expressed signal-transducing coreceptor gp130 to assemble a functional high-affinity hexameric signaling complex upon ligand engagement. Widely expressed on stromal, epithelial and hematopoietic cells, IL-11RA mediates activation of JAK/STAT (predominantly STAT3), MAPK and PI3K pathways, governing critical biological processes including hematopoiesis, tissue damage repair and immune homeostasis, and is closely linked to fibrotic disorders and tumor progression.
IL-11 R alpha분자 별명
IL-11 R alpha,IL-11 RA,IL11RA,Interleukin-11 receptor subunit alpha,IL-11 receptor subunit alpha,IL-11R subunit alpha,IL-11R-alpha
임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| Δ1-9, alanine 10, asparagine 134, recombinant human interleukin-11 | Phase 3 Clinical | Fuzhou Quanye Economic Technology Co Ltd | Thrombocytopenia | 상세 | |
| LASN-01 | LASN-01 | Phase 2 Clinical | Csl Ltd | Endocrine System Diseases; Exophthalmos; Eye Diseases; Graves Ophthalmopathy; Pulmonary Fibrosis | 상세 |
| NMX-1 | NMX-1 | Phase 2 Clinical | Novomedix LLC | Triple Negative Breast Neoplasms | 상세 |
시판 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 가장 빠른 브랜드 이름 | 가장 빠른 승인 국가 | 가장 빠른 적응증 | 가장 빠른 승인 회사 | 가장 빠른 승인 날짜 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|---|---|---|---|---|
| Oprelvekin biosimilar (Hangzhou Jiuyuan Gene Engineering) | Approved | Hangzhou Jiuyuan Gene Biomedical Co Ltd | 吉巨芬, Jijufen | Mainland China | Thrombocytopenia | Hangzhou Jiuyuan Gene Biomedical Co Ltd | 2003-09-18 | Thrombocytopenia | 상세 | |
| Recombinant human interleukin-11 (Qilu Pharmaceutical) | Approved | Qilu Pharmaceutical Co Ltd | 巨和粒 | Mainland China | Thrombocytopenia | Qilu Pharmaceutical Co Ltd | 2003-03-18 | Thrombocytopenia | 상세 | |
| Recombinant human interleukin-11 (Kerun Biopharmaceutical) | Approved | Chongqing Kerun Biologic Pharmaceutical Development Co Ltd | 百杰依 | Mainland China | Thrombocytopenia | China Resources Angde Biotech Pharma Co Ltd | 2008-05-08 | Thrombocytopenia | 상세 | |
| Recombinant human interleukin-11 (Beijing ShuangLu Pharmaceutical) | Approved | Beijing Sl Pharmaceutical Co Ltd | 迈格尔 | Mainland China | Thrombocytopenia | Beijing Sl Pharmaceutical Co Ltd | 2003-03-17 | Thrombocytopenia | 상세 | |
| Recombinant human interleukin-11 (Xiamen Amoytop Biotech) | rHuIL-11 | Approved | Xiamen Amoytop Biotech Co Ltd | 特尔康 | Mainland China | Thrombocytopenia | Xiamen Amoytop Biotech Co Ltd | 2005-04-11 | Thrombocytopenia | 상세 |
| Recombinant human interleukin 11 (BioGeneric Pharma) | Approved | Biogeneic Pharma | Thrombocytopenia | 상세 | ||||||
| Recombinant human interleukin-11 for injection | Approved | 상세 | ||||||||
| Recombinant human interleukin-11 (Shanghai CP Guojian) | Approved | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | 欣美格 | Mainland China | Thrombocytopenia | Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd | 2005-04-26 | Thrombocytopenia | 상세 | |
| Recombinant human interleukin-11 (Diao group) | Approved | Chengdu Diao Jiuhong Pharmaceutical Factory | 依星 | Mainland China | Thrombocytopenia | Chengdu Diao Jiuhong Pharmaceutical Factory | 2003-04-23 | Thrombocytopenia | 상세 |
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