언어 선택

IL-1 RAcP

IL-1 RAcP 분자 정보

영어 이름	Interleukin-1 receptor accessory protein	시판 약물 수	0
임상 약물 수	8	표적 별명	Interleukin-1 receptor 3，IL-1RAcP，IL-1 receptor accessory protein，IL-1R-3，C3orf13，Interleukin 1 Receptor Accessory Protein，IL1R3，Interleukin-1 Receptor Accessory Protein Beta，IL-1R3
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Interleukin-1 receptor accessory protein
표적 별명	Interleukin-1 receptor 3，IL-1RAcP，IL-1 receptor accessory protein，IL-1R-3，C3orf13，Interleukin 1 Receptor Accessory Protein，IL1R3，Interleukin-1 Receptor Accessory Protein Beta，IL-1R3
시판 약물 수	0
임상 약물 수	8
최고 연구 개발 단계	Phase 2 Clinical

IL-1 RAcP 제품 목록

속성
Protein (11)Cell (1)
제품 라이브러리
온라인 (12)
종
Human (8)Mouse (1)Cynomolgus (1)Rat (1)Porcine (1)
태그
His Tag (8)Fc Tag (1)His Tag & Avi Tag (1)Fc Tag & Avi Tag (1)- (1)
마커
Unconjugated (7)Biotin-labeled (2)FITC Labeled (1)PE Labeled (1)- (1)

제품 번호	종	발현 시스템	제품 설명
HOT ILP-H5225	Human	HEK293	Human IL-1 RAcP / IL-1 R3 Protein, His Tag (MALS verified)
HOT ILP-H5256	Human	HEK293	Human IL-1 RAcP / IL-1 R3 Protein, Fc Tag
HOT ILP-H82E5	Human	HEK293	Biotinylated Human IL-1 RAcP / IL-1 R3 Protein, His,Avitag™ (MALS verified)
HOT ILP-M52H5	Mouse	HEK293	Mouse IL-1 RAcP / IL-1 R3 Protein, His Tag
HOT ILP-C52H5	Cynomolgus	HEK293	Cynomolgus IL-1 RAcP / IL-1 R3 Protein, His Tag
CCHO-ATP257	Human	CHO	CHO/Human IL-1 RAcP Stable Cell Line
ILP-H52H4	Human	HEK293	Human IL-1 RAcP / IL-1 R3 Protein, His Tag, low endotoxin (MALS verified)
ILP-H82F5	Human	HEK293	Biotinylated Human IL-1 RAcP / IL-1 R3 Protein, Fc,Avitag™ (MALS verified)
ILP-HF223	Human	HEK293	FITC-Labeled Human IL-1 RAcP / IL-1 R3 Protein, His Tag
ILP-HP2H3	Human	HEK293	PE-Labeled Human IL-1 RAcP / IL-1 R3 Protein, His Tag (Site-specific conjugation)

총 수량12

IL-1 RAcP분자 배경

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

IL-1 RAcP분자 별명

IL1RAP,IL-1RAcP,C3orf13,IL1R3

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Nidanilimab	CAN-04	Phase 2 Clinical	Lund University Foundation	Biliary Tract Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Transitional Cell; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Melanoma; Myelodysplastic Syndromes; Pancreatic Neoplasms; Sarcoidosis, Pulmonary; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms	상세
CCTx-001	CCTx-001	Phase 2 Clinical	Advesya SAS	Leukemia, Myeloid, Acute; Myelodysplastic Syndromes	상세
SAR-445399	SAR-445399	Phase 2 Clinical	Sanofi	Hidradenitis Suppurativa; Immune System Diseases; Inflammation	상세
IBI-3011	IBI-3011; IBI3011	Phase 1 Clinical		Arthritis, Gouty; Gout	상세
Gene modified anti-IL1RAP Chimeric Antigen Receptor T Cells therapy(Shanghai Zhongshan Hospital)		Phase 1 Clinical	Shanghai Zhongshan Hospital	Carcinoma, Hepatocellular	상세
AK-135	AK135; AK-135	Phase 1 Clinical		Peripheral Nervous System Diseases	상세
DXP-106	DXP-106; DXP106	Phase 1 Clinical	Singlomics Biopharmaceuticals Co Ltd	Neoplasms; Solid tumours	상세
GSK-3903371	GSK-3903371; BOS-371	Clinical	Glaxosmithkline Plc	Neoplasms	상세