IgG3 Fc 분자 정보
Molecule Name
Immunoglobulin G
분자 별명
Ig gamma-3 chain C region,IgG,IgG3
Drug Development Progress
임상 약물 수8
시판 약물 수1
최고 연구 개발 단계Approved
표적 별명
Immunoglobulin G
분자 배경
Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3).
IgG3 Fc 제품 목록
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임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| Ricefidase | KJ-103; KJ103 | Phase 3 Clinical | Shanghai Bao Pharmaceuticals Co Ltd | Anti-Glomerular Basement Membrane Disease; Guillain-Barre Syndrome; Rejection of renal transplantation | 상세 |
| AT-02 | AT-02 | Phase 2 Clinical | Attralus Inc | Amyloidosis; Immunoglobulin Light-chain Amyloidosis | 상세 |
| JZB-34 | AAFP; JZB-34 | Phase 1 Clinical | Shanghai Kexin Biotech Co Ltd | Hypersensitivity | 상세 |
| Emicizumab biosimilar (Jushi Biopharmaceutical) | SYS6053; SYS-6053 | Phase 1 Clinical | Jushi Biopharmaceutical Co Ltd | Hemophilia A; Hemorrhage | 상세 |
| S-1117 | S-1117 | Phase 1 Clinical | Seismic Therapeutics Inc | Immune System Diseases | 상세 |
| BHV-1300 | BHV-1300 | Phase 1 Clinical | Biohaven Pharmaceuticals Inc | Arthritis, Rheumatoid; Graves Disease | 상세 |
| HNSA-5487 | HNSA 5487; HNSA-5487 | Phase 1 Clinical | Hansa Biopharma Ab | Autoimmune Diseases; Neoplasms | 상세 |
| Anti-CD33/anti-FcgammaRI bispecific antibody (UCSD) | Phase 1 Clinical | University Of California San Diego | Leukemia, Myeloid, Acute | 상세 |
시판 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 가장 빠른 브랜드 이름 | 가장 빠른 승인 국가 | 가장 빠른 적응증 | 가장 빠른 승인 회사 | 가장 빠른 승인 날짜 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|---|---|---|---|---|
| Imlifidase | Mac-1 | Approved | Hansamed Inc | Idefirix | EU | Rejection of renal transplantation | Hansa Biopharma Ab | 2020-08-25 | Guillain-Barre Syndrome; Kidney Diseases; Kidney Failure, Chronic; Purpura, Thrombotic Thrombocytopenic; Rejection of renal transplantation; Rejection of organ transplantation; Renal Insufficiency, Chronic | 상세 |