언어 선택

IGF-II R

IGF-II R 분자 정보

영어 이름	Insulin-like growth factor II receptor	시판 약물 수	1
임상 약물 수	0	표적 별명	Insulin-like growth factor 2 receptor，IGF-II receptor，CD222，Insulin Like Growth Factor 2 Receptor，M6P/IGF2R，M6P/IGF2 receptor，CI Man-6-P receptor，Insulin-like growth factor II receptor，IGF2R，300 KDa Mannose 6-Phosphate Receptor，MPR 300，MPRI，Cation-Independent Mannose-6-Phosphate Receptor，Cation-Independent Mannose-6 Phosphate Receptor，CD222 Antigen，CI-M6PR，MPR300，CI-MPR，CIMPR，M6P-R，MPR1，M6PR，Receptor， IGF Type 2
최고 연구 개발 단계	Approved

영어 이름	Insulin-like growth factor II receptor
표적 별명	Insulin-like growth factor 2 receptor，IGF-II receptor，CD222，Insulin Like Growth Factor 2 Receptor，M6P/IGF2R，M6P/IGF2 receptor，CI Man-6-P receptor，Insulin-like growth factor II receptor，IGF2R，300 KDa Mannose 6-Phosphate Receptor，MPR 300，MPRI，Cation-Independent Mannose-6-Phosphate Receptor，Cation-Independent Mannose-6 Phosphate Receptor，CD222 Antigen，CI-M6PR，MPR300，CI-MPR，CIMPR，M6P-R，MPR1，M6PR，Receptor， IGF Type 2
시판 약물 수	1
임상 약물 수	0
최고 연구 개발 단계	Approved

IGF-II R 제품 목록

속성
Protein (2)
제품 라이브러리
온라인 (2)
종
Human (2)
태그
His Tag (2)
마커
Unconjugated (2)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
IGR-H52H4	Human	HEK293	Human IGF-II R (43-1365) Protein, His Tag (MALS verified)
IGR-H53H3	Human	CHO	Human IGF-II R Protein, His Tag (MALS verified)

총 수량2

IGF-II R분자 배경

IGF2R, also known as the cation-independent mannose-6-phosphate receptor, is found ubiquitously in human tissues with a truncated soluble form of the receptor present in the circulation. Full-length, 300-kDa, IGF2R comprises a large N-terminal extracellular region of 15 homologous domains, a single membrane-spanning region and a small cytoplasmic tail. In addition to IGF-II binding, major IGF2R functions include sorting newly synthesized lysosomal enzymes and endocytosis of extracellular lysosomal enzymes. To perform these disparate functions, the extracellular region contains binding sites for IGF-II and phosphomannosyl residues

IGF-II R분자 별명

Cation-independent mannose-6-phosphate receptor,CI Man-6-P receptor,CI-MPR,M6PR,300 kDa mannose 6-phosphate receptor (MPR 300),Insulin-like growth factor 2 receptor,Insulin-like growth factor II receptor (IGF-II receptor),M6P/IGF2 receptor (M6P/IGF2R),CD2

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Avalglucosidase alfa	neoGAA; GZ-402666; Neo-rhGAA; NeoGAA	Approved	Genzyme Corp	Nexviazyme, Nexviadyme, 耐而赞	United States	Glycogen Storage Disease Type II	Genzyme Corp	2021-08-06	Glycogen Storage Disease Type II	상세