언어 선택

HLA-E*0103 & B2M & CMV UL40 (VMAPRTLLL)

HLA-E*0103 & B2M & CMV UL40 (VMAPRTLLL) 제품 목록

속성
Protein (2)
제품 라이브러리
온라인 (2)
종
Human (2)
태그
His Tag & Avi Tag (1)His Tag (1)
마커
Biotin-labeled (1)PE Labeled (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
HL0-H82E5	Human	HEK293	Biotinylated Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTLLL) Complex Protein (Monomer, MALS verified)
HLU-HP2H4	Human	HEK293	PE-Labeled Human HLA-E*01:03&B2M&CMV UL40 (VMAPRTLLL) Tetramer Protein

총 수량2

HLA-E*0103 & B2M & CMV UL40 (VMAPRTLLL)분자 배경

HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Trabedersen	OT-101; AP-2/09; AP-2/09-DS; AP-12009; OT-201	Phase 3 Clinical		Glioblastoma; Pancreatic Neoplasms; Coronavirus Disease 2019 (COVID-19); Mesothelioma; Astrocytoma; Colorectal Neoplasms; Lung Neoplasms; Carcinoma, Pancreatic Ductal; Melanoma; Carcinoma, Non-Small-Cell Lung	상세
Bintrafusp alfa	M-7824; GSK-4045154; MSB-0011359C	Phase 3 Clinical	Merck Serono	Brain metastases; Cholangiocarcinoma; Breast Neoplasms; Microsatellite Instability; Vulvar Neoplasms; Sarcoma; Nasopharyngeal Carcinoma; Prostatic Neoplasms; Colorectal Neoplasms; Thymus Neoplasms; Oropharyngeal Neoplasms; Gallbladder Neoplasms; Lung Neoplasms; Prostatic Neoplasms, Castration-Resistant; Lymphoma; Penile Neoplasms; Thymoma; Urogenital Neoplasms; Metastatic breast cancer; Carcinoma, Small Cell; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Melanoma; Neoplasm Metastasis; Sarcoma, Kaposi; Neoplasms, Germ Cell and Embryonal; Stomach Neoplasms; Solid tumours; Hematologic Neoplasms; Head and Neck Neoplasms; Intestinal Neoplasms; Skin Melanoma; Squamous Cell Carcinoma of Head and Neck; Rectal Neoplasms; Vaginal Neoplasms; Carcinoma; Carcinoma, Renal Cell; Esthesioneuroblastoma, Olfactory; Anus Neoplasms; Biliary Tract Neoplasms; Neoplasms; Triple Negative Breast Neoplasms; Colonic Neoplasms; Pancreatic Neoplasms; Nose Neoplasms; Ganglioglioma; Papillomavirus Infections; Carcinoma, Trans	상세
Nisevokitug	NIS-793	Phase 3 Clinical	Xoma Corp	Kidney Neoplasms; Polycythemia Vera; Pancreatic Neoplasms; Myelodysplastic Syndromes; Breast Neoplasms; Colorectal Neoplasms; Primary Myelofibrosis; Carcinoma, Pancreatic Ductal; Lung Neoplasms; Adenocarcinoma; Thrombocythemia, Essential; Carcinoma, Hepatocellular	상세
ENERGI-F701	ENERGI-F701	Phase 2 Clinical	Energenesis Biomedical Co Ltd	Alopecia	상세
LP-008	LP-008	Phase 1 Clinical		Solid tumours	상세