언어 선택

HLA-A*1101 & B2M & KRASG12S (VVVGASGVGK)

HLA-A*1101 & B2M & KRASG12S (VVVGASGVGK) 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag & Avi Tag (1)
마커
Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
HLS-H82E8	Human	HEK293	Biotinylated Human HLA-A*11:01&B2M&KRASG12S (VVVGASGVGK) Complex Protein (Monomer, MALS verified)

총 수량1

HLA-A*1101 & B2M & KRASG12S (VVVGASGVGK)분자 배경

The peptide VVVGASGVGK, derived from the KRAS G12S mutation and presented by the HLA-A*11:01/β2-microglobulin (β2m) complex, is a pivotal antigenic target in antitumor immunity. This complex plays a crucial role by activating specific cytotoxic T lymphocytes (CTLs), enabling the immune system to recognize and eliminate tumor cells harboring the KRAS G12S mutation.

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Paltusotine	CRN-00808	Phase 3 Clinical	Crinetics Pharmaceuticals Inc	Acromegaly; Malignant Carcinoid Syndrome; Neuroendocrine Tumors	상세
Lutetium-177 labelled edotreotide	ITM-11	Phase 3 Clinical	Universitaetsspitals Basel, Itm Solucin Gmbh	Solid tumours; Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors; Central Nervous System Neoplasms; Thymus Neoplasms; Lung Neoplasms; Lymphoma; Carcinoma, Neuroendocrine	상세
RYZ-101	RYZ-101	Phase 3 Clinical		Carcinoid Tumor; Stomach Neoplasms; Pancreatic neuroendocrine tumors (pNET); Small Cell Lung Carcinoma; Neuroendocrine Tumors; Carcinoma, Neuroendocrine; Gastrointestinal Neoplasms	상세
Gallium-68 satoreotide	68Ga-OPS-202; 68Ga IPN-1070; 68Ga-DOTA-JR11	Phase 2 Clinical	Ipsen Inc	Stomach Neoplasms; Pancreatic neuroendocrine tumors (pNET); Small Cell Lung Carcinoma; Breast Neoplasms; Gastrointestinal Neoplasms	상세
Nendratareotide uzatansine	BTP-277; PEN-221	Phase 2 Clinical	Tarveda Therapeutics Inc	Small Cell Lung Carcinoma; Neuroendocrine Tumors; Carcinoma, Neuroendocrine	상세
Yttrium 90-labelled edotreotide	SMT-487-[90Y]; DOTATOC-[90Y]	Phase 2 Clinical	The University Of Iowa, Novartis Pharma Ag	Central Nervous System Neoplasms; Meningioma; Melanoma; Lymphoma; Lung Neoplasms; Sarcoma; Neuroblastoma; Breast Neoplasms; Brain Neoplasms; Solid tumours; Neuroendocrine Tumors; Small Cell Lung Carcinoma; Adenoma, Islet Cell; Neoplasms; Pheochromocytoma; Carcinoid Tumor; Medulloblastoma	상세
Dopastatin	TBR-760; BIM-23A760	Phase 2 Clinical	Ipsen	Acromegaly; Malignant Carcinoid Syndrome; Adenoma; Pituitary Neoplasms	상세
ZT-01	ZT 01; ZT-01	Phase 2 Clinical	Tulane University, York University, University Of Toronto, Toronto	Diabetes Mellitus, Type 1; Hypoglycemia	상세
Re-188 P 2045	P2045; BAY-865284; Rhenium-188 P2045; Re-188 P 2045; Rh-188 P2045; Rhenium-188-P-2045	Phase 2 Clinical	Bayer AG	Neoplasm Recurrence, Local; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Lung Neoplasms; Carcinoma, Small Cell; Carcinoma, Non-Small-Cell Lung	상세
[203-Pb] VMT-NET	[203-Pb] VMT-NET	Phase 2 Clinical	Perspective Therapeutics Inc	Head and Neck Neoplasms; Pheochromocytoma; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Neuroendocrine Tumors; Paraganglioma	상세
64Cu-SarTate		Phase 2 Clinical	University Of Melbourne	Neuroendocrine Tumors; Neuroblastoma; Meningioma	상세
Lutetium-177 DOTA satoreotide	[177Lu]LuSSO110; 177Lu-IPN-1072; OPS-201; 177Lu-IPN01072; 177LU-OPS 201; 177Lu-DOTA- JR11; 177Lu-satoreotide	Phase 1 Clinical	Ipsen, OctreoPharm Sciences GmbH	Small Cell Lung Carcinoma; Breast Neoplasms; Meningioma	상세
CRN-01941	CRN-01941	Phase 1 Clinical	Crinetics Pharmaceuticals Inc		상세
68Ga-NOTA-3PTATE-RGD	68Ga-NOTA-3PTATE-RGD; 68Ga-NOTA-3P-TATE-RGD	Phase 1 Clinical	Peking Union Medical College Hospital	Small Cell Lung Carcinoma; Neuroendocrine Tumors; Lung Neoplasms	상세
[99mTc]Tc-TECANT1		Phase 1 Clinical	Ljubljana University Medical Centre, Medical University Of Innsbruck, Narodowe Centrum Badan Jadrowych, Jagiellonian University Sylff Fellows Association	Neuroendocrine Tumors	상세
161Tb-DOTA-LM3	161Tb-DOTA-LM3	Phase 1 Clinical	University Hospital Basel	Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors	상세
44Sc-edotreotide	44Sc-edotreotide; 44Sc-DOTA-[3-Tyr]-octreotide; Sc44-DOTATOC	Clinical	Zentralklinik Bad Berka	Diagnostic agents	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Pasireotide Pamoate		Approved	Novartis Pharma Ag	Signifor lar	United States	Acromegaly	Recordati Rare Diseases Inc	2014-12-15	Gigantism; Acromegaly; Cushing Syndrome; Carcinoid Tumor; Pituitary ACTH Hypersecretion; Neuroendocrine Tumors; Meningioma	상세
Lutetium (177Lu) oxodotreotide	Lu-DOTATATE; Lutetium (177Lu) DOTA-TATE; 177Lu-DOTATATE; [Lu-177]-DOTATATE; AAA-601; F-1515; XTR-008; [177Lu]Lu-DOTA-TATE	Approved		Lutathera	EU	Neuroendocrine Tumors	Advanced Accelerator Applications Sa	2017-09-26	Breast Neoplasms; Carcinoid Heart Disease; Meningioma; Paraganglioma; Metastatic breast cancer; Lung Neoplasms; Carcinoma, Neuroendocrine; Pituitary Neoplasms; Medullary thyroid cancer (MTC); Neuroblastoma; Prostatic Neoplasms; Liver Neoplasms; Neuroendocrine Tumors; Malignant Carcinoid Syndrome; Pancreatic neuroendocrine tumors (pNET); Pancreatic Neoplasms; Adenoma, Islet Cell; Bronchial Neoplasms; Carcinoid Tumor; Pheochromocytoma; Leiomyosarcoma	상세
Vapreotide Acetate	RC-160; BMY-41606	Approved	Debiopharm Group	Sanvar, Docrised, Sanvar IR, Sanvar SR					Acromegaly; Hypertension, Portal; Pancreatic Neoplasms; Hemorrhage; Neuroendocrine Tumors; Diarrhea; Intraoperative Complications; Postoperative Complications; Esophageal and Gastric Varices; Crohn Disease	상세
Pasireotide Diaspartate	SOM-230; SOM-230C; SOM-320	Approved	Novartis Pharma Ag	Signifor, 丝尼芬	EU	Cushing Syndrome	Recordati Rare Diseases Inc	2012-04-24	Pituitary Neoplasms; Uveal melanoma; Prostatic Neoplasms, Castration-Resistant; Cysts; Pituitary ACTH Hypersecretion; Medullary thyroid cancer (MTC); Prostatic Neoplasms; Hyperinsulinism; Nelson Syndrome; Multiple Myeloma; Thyroid Neoplasms; Thymoma; Meningioma; Prolactinoma; Gastrointestinal Neoplasms; Carcinoma, Hepatocellular; Cluster Headache; Acromegaly; Neuroendocrine Tumors; Liver Cirrhosis; Kidney Diseases; Small Cell Lung Carcinoma; Pancreatic Neoplasms; Neoplasms; Adenoma, Islet Cell; Hypoglycemia; Dumping Syndrome; Insulinoma; Carcinoid Tumor; Cushing Syndrome; Alcohol-Induced Disorders; Congenital Hyperinsulinism; ACTH Syndrome, Ectopic	상세
Ga-68 Edotreotide	SMT-487; [68Ga]DOTATOC; 90Y-DOTATOC	Approved		SomaKit TOC, Gallium Dotatoc Ga 68, TOCscan	EU	Diagnostic agents; Neuroendocrine Tumors; Pancreatic neuroendocrine tumors (pNET)	Advanced Accelerator Applications Sa	2016-12-08	Medulloblastoma; Multiple Endocrine Neoplasia Type 1; Carcinoid Tumor; Pancreatic neuroendocrine tumors (pNET); Neuroendocrine Tumors; Neuroblastoma; Pituitary Neoplasms; Diagnostic agents; von Hippel-Lindau Disease; Somatostatinoma; Meningioma; Paraganglioma	상세
Gallium (68Ga) oxodotreotide	68Ga-DOTA-TATE; 68-Ga-DOTA-TATE	Approved		Netspot	United States	Neuroendocrine Tumors	Aaa Usa Inc	2016-06-01	Pheochromocytoma; Carcinoid Tumor; Pancreatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Neuroendocrine Tumors; Prostatic Neoplasms; Thyroid Neoplasms; Carcinoma, Neuroendocrine; von Hippel-Lindau Disease; Paraganglioma; Carcinoma, Hepatocellular	상세