언어 선택

GM-CSF R alpha

GM-CSF R alpha 분자 정보

영어 이름	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha	시판 약물 수	0
임상 약물 수	4	표적 별명	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha
표적 별명	GM-CSF-R-alpha，GMCSFR-alpha，GMR-alpha，CD116，Colony Stimulating Factor 2 Receptor Subunit Alpha，Colony Stimulating Factor 2 Receptor， Alpha， Low-Affinity (Granulocyte-Macrophage)，CSF2R，CSF2RAX，CSF2RAY，CSF2RX，CSF2RY，GM-CSF Receptor Alpha Subunit，GMCSFR，GMR，Granulocyte-Macrophage Colony-Stimulating Factor Receptor Alpha Chain，SMDP4，Colony Stimulating Factor 2 Receptor Alpha Subunit，CDw116，CD116 Antigen，Alpha-GM-CSF Receptor，AlphaGMR
시판 약물 수	0
임상 약물 수	4
최고 연구 개발 단계	Phase 3 Clinical

GM-CSF R alpha 제품 목록

속성
Protein (3)
제품 라이브러리
온라인 (3)
종
Human (2)Mouse (1)
태그
His Tag (2)Fc Tag (1)
마커
Unconjugated (3)

제품 번호	종	발현 시스템	제품 설명
HOT GRA-H52H7	Human	HEK293	Human GM-CSF R alpha Protein, His Tag (SPR verified)
GRA-H5255	Human	HEK293	Human GM-CSF R alpha Protein, Fc Tag
GMA-M52H3	Mouse	HEK293	Mouse GM-CSF R alpha Protein, His Tag

총 수량3

GM-CSF R alpha분자 배경

GM-CSF R alpha(Granulocyte-macrophage colony-stimulating factor receptor subunit alpha) is also known as CSF2RA, CD116, GMR-alpha. Low affinity receptor for granulocyte-macrophage colony-stimulating factor. Transduces a signal that results in the proliferation, differentiation, and functional activation of hematopoietic cells. Hereditary pulmonary alveolar proteinosis (hPAP) is a rare disorder of pulmonary surfactant accumulation and hypoxemic respiratory failure caused by mutations in CSF2RA (encoding the granulocyte/macrophage colony-stimulating factor [GM-CSF] receptor α-chain [CD116]), which results in reduced GM-CSF-dependent pulmonary surfactant clearance by alveolar macrophages.

GM-CSF R alpha분자 별명

GM-CSF R alpha,GM-CSF-R-alpha,GMCSFR-alpha,GMR-alpha,CSF2RA,CSF2R,CSF2RY,CDw116,CD116

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Mavrilimumab	CAM-3001; KPL-301; GM-CSFR; CAM3001	Phase 3 Clinical	Csl Ltd	Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19); Giant Cell Arteritis; Pneumonia	상세
Anti-GMR CAR T-cell Therapy		Phase 2 Clinical	Kyoto Prefectural University Of Medicine, Shinshu University School of Medicine	Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Juvenile	상세
CSF2RA gene-corrected macrophages(University of South Florida)		Phase 2 Clinical	Russian Academy Of Medical Sciences	Pulmonary Alveolar Proteinosis	상세
STSA-1005	STSA-1005; STSA1005	Phase 1 Clinical	Staidson(Beijing) Biopharmaceuticals Co Ltd	Coronavirus Disease 2019 (COVID-19)	상세