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Glutaredoxin 1

Glutaredoxin 1 Overview

English Name	Glutaredoxin	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	Glutaredoxin-1，Thioltransferase，GRX，GLRX，Glutaredoxin，Thioltransferase-1，TTase-1，Glutaredoxin (Thioltransferase)，GRX1，Glutaredoxins
Highest Development Stage	Phase 2 Clinical

English Name	Glutaredoxin
Target Synonym	Glutaredoxin-1，Thioltransferase，GRX，GLRX，Glutaredoxin，Thioltransferase-1，TTase-1，Glutaredoxin (Thioltransferase)，GRX1，Glutaredoxins
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 2 Clinical

Glutaredoxin 1 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
GLX-H5149	Human	E. coli	Human Glutaredoxin 1 / GLRX1 Protein, His Tag

Total: 1

Glutaredoxin 1 Background

Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.

Glutaredoxin 1 Synonyms

GLRX,GRX,TTase-1,GLRX1,GRX1

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Dimesna	NSC-716976; BNP-7787; LP-300	Phase 2 Clinical	Bionumerik	Adenocarcinoma of Lung; Anemia; Breast Diseases; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Drug-Related Side Effects and Adverse Reactions; Lung Neoplasms; Neoplasm Metastasis; Neutropenia	Details