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홈 페이지모든 분자gH&gL
gH&gL
gH&gL 제품 목록
- 속성
Antibody (1)
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Mouse (1)
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- (1)
- 마커
Unconjugated (1)
| 제품 번호 | 종 | 발현 시스템 | 제품 설명 | 단백질 구조 | 순도 | 특성 |
|---|---|---|---|---|---|---|
GHL-MY2111 |  Mouse | HEK293 | Monoclonal Anti-VZV gH & gL Antibody, Human IgG1 (4F12) (MALS verified) |  |
총 수량1
- 1
gH&gL분자 배경
Varicella-zoster virus (VZV) is the alphaherpesvirus that causes chicken pox (varicella) and shingles (zoster). As for all herpesviruses, VZV relies on a fusion complex comprised of three core glycoproteins, gB, gH and gL, required for entry of virions into host cells. VZV ORFs 37 and 60 encode gH (841aa; 118 kDa) and gL (160aa; 20 kDa), respectively, which are N- and O-linked glycosylated and form a heterodimer that is necessary for the activation of gB.
임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| XCUR-17 | XCUR-17 | Phase 1 Clinical | Exicure Inc | Psoriasis | 상세 |
시판 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 가장 빠른 브랜드 이름 | 가장 빠른 승인 국가 | 가장 빠른 적응증 | 가장 빠른 승인 회사 | 가장 빠른 승인 날짜 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|---|---|---|---|---|
| Brodalumab | IL-17R mAb; MEDI-6365; KHK-4827; AMG-827 | Approved | Amgen Inc | Siliq, Lumicef, Kyntheum, 立美芙 | Japan | Psoriasis; Arthritis, Psoriatic | Kyowa Kirin Co Ltd | 2016-07-04 | Non-radiographic axial spondyloarthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Scleroderma, Systemic; Psoriasis; Asthma; Arthritis, Psoriatic; Hidradenitis Suppurativa; Crohn Disease; Plaque psoriasis | 상세 |
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