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GAS6

GAS6 Overview

English Name	Growth arrest-specific protein 6	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	GAS6，AXLLG，Growth Arrest Specific 6，AXL Receptor Tyrosine Kinase Ligand，AXL Stimulatory Factor，Growth Arrest-Specific Protein 6，GAS-6，AXSF，FLJ34709，DKFZp666G247
Highest Development Stage	Phase 3 Clinical

English Name	Growth arrest-specific protein 6
Target Synonym	GAS6，AXLLG，Growth Arrest Specific 6，AXL Receptor Tyrosine Kinase Ligand，AXL Stimulatory Factor，Growth Arrest-Specific Protein 6，GAS-6，AXSF，FLJ34709，DKFZp666G247
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 3 Clinical

GAS6 Product List

Product Category
Protein (3)
Product Status
Launched (3)
Species
Human (3)
Tag
His Tag (3)
Conjugate
Unconjugated (3)

Cat. No.	Species	Host	Product Description
HOT GA6-H5246	Human	HEK293	Human GAS6 (49-678) Protein, His Tag
GA6-H5247	Human	HEK293	Human GAS6 (471-678) Protein, His Tag (MALS verified)
GA6-H5249	Human	HEK293	Human GAS6 (279-678) Protein, His Tag (MALS verified)

Total: 3

GAS6 Background

GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG. Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.

GAS6 Synonyms

GAS6,GAS-6,AXLLG

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Batiraxcept	S6-500c; 3D-229; 3D229; 3D-299; Ruga-S6; AB-007; AVB 500; AVB-500; Aravive S-6; AVB-S6-500	Phase 3 Clinical	Aravive Inc	Carcinoma, Ovarian Epithelial; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Fallopian Tube Neoplasms; Glomerulonephritis, IGA; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Solid tumours; Uterine Neoplasms	Details