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FGF acidic

FGF acidic 분자 정보

영어 이름	Fibroblast growth factor 1	시판 약물 수	0
임상 약물 수	2	표적 별명	Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Fibroblast growth factor 1
표적 별명	Fibroblast Growth Factor 1 (Acidic)，HBGF1，Acidic fibroblast growth factor，Heparin-binding growth factor 1，HBGF-1，Endothelial cell growth factor，FGF1，Fibroblast Growth Factor 1，Endothelial Cell Growth Factor， Alpha，Endothelial Cell Growth Factor， Beta，FGF-1，AFGF，FGFA，ECGF，Beta-Endothelial Cell Growth Factor，ECGF-Beta，FGF-Alpha，GLIO703，ECGFA，ECGFB
시판 약물 수	0
임상 약물 수	2
최고 연구 개발 단계	Phase 3 Clinical

FGF acidic 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
Tag Free (1)
마커
Unconjugated (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
AFF-H4116	Human	E. coli	Human FGF acidic Protein, Tag Free

총 수량1

FGF acidic분자 배경

Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF acidic is a potent growth factor for fibroblasts and endothelial cells. FGF acidic is involved in wound repair, angiogenesis, and development. FGF acidic is secreted from cells via an endoplasmic reticulum/Golgi independent mechanism. The ability of FGF acidic to bind to heparin sulfate is required for its ability to interact with FGF receptors and induce signaling. There are four distinct FGF receptors and each has multiple splice variants. FGF acidic binds with high affinity to many, but not all, FGFRs. Signaling cascades activated through FGF basic binding to FGFR include the ras-raf-MAPK, PLCγ/PKC, and PI3K/Akt pathways.

FGF acidic분자 별명

FGF1,AFGF,ECGF,ECGF-beta,ECGFA,ECGFB,FGF-alpha,FGFA,GLIO703,HBGF1

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Muparfostat sodium	PI-88	Phase 3 Clinical	Australian National University	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Liver Neoplasms; Lung Neoplasms; Melanoma; Neoplasms; Prostatic Neoplasms; Skin Melanoma; Solid tumours	상세
TTHX-1114	TTHX-1114; NM-141; NM141; TTHX1114	Phase 2 Clinical	Florida State University	Corneal Diseases; Corneal Dystrophies, Hereditary; Fuchs' Endothelial Dystrophy; Vascular Diseases	상세