FGF-5

Fibroblast growth factor-5 (FGF5) is a member of the fibroblast growth factor (FGF) family and acts as a crucial regulator of hair growth and an oncogenic factor in several human cancers. Generally, Fibroblast growth factor 5 (FGF5) is widely expressed in embryonic but scarcely in adult tissues. Overexpression of FGF5 has been associated with prostate cancer, pancreatic cancer, breast cancer, renal cell carcinoma, etc. it was confirmed that FGF5 contributes to the malignant progression of human astrocytic brain tumors by both autocrine and paracrine effects.