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FGF-4

FGF-4 분자 정보

영어 이름	Fibroblast growth factor 4	시판 약물 수	0
임상 약물 수	1	표적 별명	Fibroblast Growth Factor 4 Splice Isoform，Oncogene HST，K-FGF，KFGF，KS3，HBGF-4，Heparin-binding growth factor 4，HST，HSTF1，Fibroblast growth factor 4，FGF4，FGF-4，Transforming Protein KS3，Human Stomach Cancer， Transforming Factor From FGF-Related Oncogene，Heparin Secretory Transforming Protein 1，Kaposi Sarcoma Oncogene，HSTF-1，HST-1，Heparin Secretory-Transforming Protein 1
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Fibroblast growth factor 4
표적 별명	Fibroblast Growth Factor 4 Splice Isoform，Oncogene HST，K-FGF，KFGF，KS3，HBGF-4，Heparin-binding growth factor 4，HST，HSTF1，Fibroblast growth factor 4，FGF4，FGF-4，Transforming Protein KS3，Human Stomach Cancer， Transforming Factor From FGF-Related Oncogene，Heparin Secretory Transforming Protein 1，Kaposi Sarcoma Oncogene，HSTF-1，HST-1，Heparin Secretory-Transforming Protein 1
시판 약물 수	0
임상 약물 수	1
최고 연구 개발 단계	Phase 3 Clinical

FGF-4 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag (1)
마커
Unconjugated (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
FG4-H51H3	Human	E. coli	Human FGF-4 Protein, His Tag

총 수량1

FGF-4분자 배경

Fibroblast growth factor-4 (FGF4) is expressed in embryonic stages and in adult tissues, where it plays critical roles in modulating multiple cellular functions. Fibroblast growth factor 4 (FGF4) is a multipotent growth factor and is highly expressed in various human cancers. In lung adenocarcinoma (ADC) cell lines, FGF4 could alter cell morphology, promote epithelial-mesenchymal transition-associated protein expression, and enhance cell proliferation, migration/invasion and colony initiation. In B-cell lymphoma, FGF4 secretion by cancer cells induces Jag1 expression in neighbor Endothelial cell that in turn activates Notch2 in lymphoma cells.