Fc gamma RI / CD64

Fc gamma RI / CD64 분자 정보

영어 이름High affinity immunoglobulin gamma Fc receptor I시판 약물 수0
임상 약물 수0표적 별명IgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)
최고 연구 개발 단계Preclinical
영어 이름High affinity immunoglobulin gamma Fc receptor I
표적 별명IgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)
시판 약물 수0
임상 약물 수0
최고 연구 개발 단계Preclinical

Fc gamma RI / CD64분자 배경

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses. High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

Fc gamma RI / CD64분자 별명

FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI

제품 리뷰

  • g***t2025-11-29
    0사람들이 좋아합니다
    Very good product for SPR analyses with antibodies
  • H***n2023-05-03
    0사람들이 좋아합니다
    I used Acro's Fc gamma receptors to build several new antibody binding assays. The proteins arrived promptly, sometimes within a few days of placing the orders. The proteins were also high quality, with no background or issues with stability. I have continued to use them for months with no issues. These produced high quality and robust data with minimal assay development. I would highly recommend this product.
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