언어 선택

ENPP-2

ENPP-2 분자 정보

영어 이름	Ectonucleotide pyrophosphatase/phosphodiesterase 2	시판 약물 수	0
임상 약물 수	9	표적 별명	EC:3.1.4.39，ATX，Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2，Phosphodiesterase I/Nucleotide Pyrophosphatase 2，Plasma Lysophospholipase D，Autotaxin-T，EC 3.1.4.39，PD-IALPHA，ATX-X，NPP2，E-NPP 2，Autotaxin，ENPP2，PDNP2，Ectonucleotide Pyrophosphatase/Phosphodiesterase 2，Extracellular Lysophospholipase D，LysoPLD
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Ectonucleotide pyrophosphatase/phosphodiesterase 2
표적 별명	EC:3.1.4.39，ATX，Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 2，Phosphodiesterase I/Nucleotide Pyrophosphatase 2，Plasma Lysophospholipase D，Autotaxin-T，EC 3.1.4.39，PD-IALPHA，ATX-X，NPP2，E-NPP 2，Autotaxin，ENPP2，PDNP2，Ectonucleotide Pyrophosphatase/Phosphodiesterase 2，Extracellular Lysophospholipase D，LysoPLD
시판 약물 수	0
임상 약물 수	9
최고 연구 개발 단계	Phase 2 Clinical

ENPP-2 제품 목록

속성
Protein (1)
제품 라이브러리
온라인 (1)
종
Human (1)
태그
His Tag (1)
마커
Unconjugated (1)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
EN2-H5241	Human	HEK293	Human ENPP-2 / Autotaxin Protein, His Tag (active enzyme)

총 수량1

ENPP-2분자 배경

Autotaxin also known as ectonucleotide pyrophosphatase / phosphodiesterase family member 2 (E-NPP 2 or ENPP2), Extracellular lysophospholipase D (LysoPLD), Autotaxin (ATX or ATX-X), which belongs to the nucleotide pyrophosphatase / phosphodiesterase family. ENPP2 contains two SMB (somatomedin-B) domains. ENPP2 hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. ENPP2 can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. ENPP2 stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein.

ENPP-2분자 별명

ENPP-2,E-NPP 2,Autotaxin,LysoPLD,ATX,PDNP2,ATX-X,NPP2,PD-IALPHA

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
BBT-877	BBT-877	Phase 2 Clinical	Legochem	Idiopathic Pulmonary Fibrosis	상세
Cambritaxestat	CRT-0273750; IOA-289	Phase 2 Clinical	Cancer Research Technology, Merck & Co	Pancreatic Neoplasms; Solid tumours	상세
HRS-9813	HRS-9813; HRS9813	Phase 2 Clinical	Guangdong Hengrui Pharmaceutical Co Ltd	Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis	상세
HW-021199	HW-021199	Phase 2 Clinical	Hubei Bio-Pharmaceutical Industrial Technological Institute Inc, Humanwell Puracap (Likang) Pharmaceuticals Co Ltd	Idiopathic Pulmonary Fibrosis	상세
HNC664	HNC664; HNC-664	Phase 1 Clinical	Guangzhou Henovcom Bioscience Co Ltd	Idiopathic Pulmonary Fibrosis; Pancreatic Neoplasms	상세
Cudetaxestat	PAT-409; BLD-0409	Phase 1 Clinical	Blade Therapeutics Inc	Idiopathic Pulmonary Fibrosis; Liver Diseases; Metabolic Dysfunction-Associated Steatotic Liver Disease	상세
NXC-680	NXC-680	Phase 1 Clinical	Nextgen Bioscience Inc	Idiopathic Pulmonary Fibrosis	상세
HNC-1058	HNC-1058	Phase 1 Clinical	Guangzhou Henovcom Bioscience Co Ltd	Idiopathic Pulmonary Fibrosis	상세
FTP-198	FTP-198	Phase 1 Clinical	Haisco Pharmaceutical Group Co Ltd	Idiopathic Pulmonary Fibrosis	상세