언어 선택

EMMPRIN

EMMPRIN 분자 정보

영어 이름	Basigin	시판 약물 수	1
임상 약물 수	4	표적 별명	BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen
최고 연구 개발 단계	Approved

영어 이름	Basigin
표적 별명	BSG，Extracellular matrix metalloproteinase inducer，UNQ6505/PRO21383，Basigin (Ok Blood Group)，Tumor Cell-Derived Collagenase Stimulatory Factor，Leukocyte Activation Antigen M6，Collagenase Stimulatory Factor，Basigin，5F7，Ok Blood Group，CD147 Antigen，EMPRIN，CD147，OK，TCSF，EMMPRIN，SLC7A11，OK blood group antigen
시판 약물 수	1
임상 약물 수	4
최고 연구 개발 단계	Approved

EMMPRIN 제품 목록

속성
Protein (6)
제품 라이브러리
온라인 (6)
종
Human (4)Mouse (1)Cynomolgus (1)
태그
His Tag (3)Fc Tag (1)His Tag & Avi Tag (2)
마커
Unconjugated (3)Biotin-labeled (2)FITC Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT CD7-H5222	Human	HEK293	Human EMMPRIN / CD147 Protein, His Tag (MALS verified)
HOT CD7-H82E0	Human	HEK293	Biotinylated Human EMMPRIN / CD147 Protein, Avitag™,His Tag (MALS verified)
HOT CD7-M82E8	Mouse	HEK293	Biotinylated Mouse EMMPRIN / CD147 Protein, His,Avitag™ (MALS verified)
CD7-H5259	Human	HEK293	Human EMMPRIN / CD147 Protein, Fc Tag
CD7-HF222	Human	HEK293	FITC-Labeled Human EMMPRIN / CD147 Protein, His Tag
CD7-C52H8	Cynomolgus	HEK293	Cynomolgus EMMPRIN / CD147 Protein, His Tag (MALS verified)

총 수량6

EMMPRIN분자 배경

CD147, also known as Basigin (BSG), or extracellular matrix metalloproteinase inducer (EMMPRIN). The human basigin protein contains 269 amino acids that form two heavily glycosylated C2 type immunoglobulin-like domains at the N-terminal extracellular portion. A second form of basigin has also been characterized that contains one additional immunoglobulin-like domain in its extracellular portion. As members of the immunoglobulin superfamily play fundamental roles in intercellular recognition involved in various immunologic phenomena, differentiation, and development, basigin is thought also to play a role in intercellular recognition and regulate several distinct functions, such as spermatogenesis, expression of the monocarboxylate transporter and the responsiveness of lymphocytes. Basigin is a type I integral membrane receptor that has many ligands, including the cyclophilin (CyP) proteins Cyp-A and CyP-B and certain integrins.

EMMPRIN분자 별명

Basigin,BSG,5F7,CD147,EMMPRIN,M6,OK,TCSF

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Mertuzumab		Phase 3 Clinical	Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd.	Carcinoma, Non-Small-Cell Lung; Coronavirus Disease 2019 (COVID-19)	상세
Meplazumab	HI6H8	Phase 3 Clinical	Institute Of Medicine Fourth Military Medical University, Jiangsu Pacific Minok Biopharmaceutical Co., Ltd.	Coronavirus Disease 2019 (COVID-19); Malaria; Malaria, Falciparum; Post-Acute COVID-19 Syndrome	상세
humanized ADCC cHAb18 antibody (Pacific Meinuoke/Fourth Military Medical University)		Phase 1 Clinical	Air Force Medical University	Carcinoma, Non-Small-Cell Lung	상세
CD147-CAR T cell therapy (Peking University People's Hospital)		Phase 1 Clinical	Peking University People'S Hospital	Lymphoma, T-Cell	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Iodine[131I] Metuximab		Approved	Chengdu Huasun Biotechnology Co Ltd	Licartin, 利卡汀	Mainland China	Carcinoma, Hepatocellular	Chengdu Huasun Biotechnology Co Ltd	2006-10-12	Carcinoma, Hepatocellular	상세