언어 선택

DNAM-1

DNAM-1 분자 정보

영어 이름	CD226 antigen	시판 약물 수	0
임상 약물 수	0	표적 별명	DNAX accessory molecule 1，DNAM-1，T Lineage-Specific Activation Antigen 1 Antigen，PTA1，DNAX Accessory Molecule-1，Adhesion Glycoprotein，TLiSA1，DNAM1，CD226 Molecule，Platelet And T Cell Activation Antigen 1
최고 연구 개발 단계	Preclinical

영어 이름	CD226 antigen
표적 별명	DNAX accessory molecule 1，DNAM-1，T Lineage-Specific Activation Antigen 1 Antigen，PTA1，DNAX Accessory Molecule-1，Adhesion Glycoprotein，TLiSA1，DNAM1，CD226 Molecule，Platelet And T Cell Activation Antigen 1
시판 약물 수	0
임상 약물 수	0
최고 연구 개발 단계	Preclinical

DNAM-1 제품 목록

속성
Protein (5)
제품 라이브러리
온라인 (5)
종
Human (3)Cynomolgus (1)Mouse (1)
태그
His Tag (3)Fc Tag (1)Fc Tag & Avi Tag (1)
마커
Unconjugated (4)Biotin-labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT DN1-H5257	Human	HEK293	Human DNAM-1 / CD226 Protein, Fc Tag (MALS verified)
HOT DN1-H52H6	Human	HEK293	Human DNAM-1 / CD226 Protein, His Tag
HOT DN1-H82F9	Human	HEK293	Biotinylated Human DNAM-1 / CD226 Protein, Fc,Avitag™
HOT DN1-M52H5	Mouse	HEK293	Mouse DNAM-1 / CD226 Protein, His Tag (SPR verified)
DN1-C52H9	Cynomolgus	HEK293	Cynomolgus DNAM-1 / CD226 Protein, His Tag

총 수량5

DNAM-1분자 배경

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.