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DLL1

DLL1 분자 정보

영어 이름	Delta Like Canonical Notch Ligand 1	시판 약물 수	0
임상 약물 수	0	표적 별명	Delta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
최고 연구 개발 단계	Preclinical

영어 이름	Delta Like Canonical Notch Ligand 1
표적 별명	Delta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
시판 약물 수	0
임상 약물 수	0
최고 연구 개발 단계	Preclinical

DLL1 제품 목록

속성
Protein (3)Cell Grade Beads (2)
제품 라이브러리
온라인 (5)
종
Human (3)- (2)
태그
His Tag (1)His Tag & Avi Tag (1)- (2)Fc Tag (1)
마커
Unconjugated (2)Biotin-labeled (1)- (2)

제품 번호	종	발현 시스템	제품 설명
HOT DL1-H52H8	Human	HEK293	Human DLL1 / Delta1 Protein, His Tag, premium grade
HOT DL1-H82E5	Human	HEK293	Biotinylated Human DLL1 / Delta1 Protein, His,Avitag™, premium grade
HOT MBS-C040	-	-	ActiveMax® Human DLL1 μBeads, premium grade (for cells, 5.5μm)
DL1-H5259	Human	HEK293	Human DLL1 / Delta1 Protein, Fc Tag, premium grade
MBS-C041	-	-	ActiveMax® Human DLL1 μBeads, premium grade (for cells, 20 μm)

총 수량5

DLL1분자 배경

Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.