CXCR5 분자 정보
Molecule Name
C-X-C motif chemokine receptor 5
분자 별명
BLR1, CD185, MDR15
Drug Development Progress
임상 약물 수2
시판 약물 수0
최고 연구 개발 단계Phase 2 Clinical
표적 별명
Burkitt Lymphoma Receptor 1， GTP-Binding Protein，C-X-C Motif Chemokine Receptor 5，Burkitt Lymphoma Receptor 1， GTP Binding Protein (Chemokine (C-X-C Motif) Receptor 5)，Chemokine (C-X-C Motif) Receptor 5，Monocyte-Derived Receptor 15，MDR-15，C-X-C Chemokine Receptor Type 5，Burkitt Lymphoma Receptor 1，CD185 Antigen，CXCR-5，CD185，MDR15，BLR1，CXCR5，CXC-R5，Receptors， CXCR5
분자 배경
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
CXCR5 제품 목록
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임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| PF-06835375 | PF-06835375 | Phase 2 Clinical | Pfizer Inc | Arthritis, Rheumatoid; Lupus Erythematosus, Systemic; Lupus Vulgaris; Purpura, Thrombocytopenic, Idiopathic | 상세 |
| CXCR5 Modified EGFR Chimeric Antigen Receptor Autologous T Cell Therapy | Phase 1 Clinical | Second Affiliated Hospital Of Guangzhou Medical University | Carcinoma, Non-Small-Cell Lung | 상세 |