Clusterin

Clusterin 분자 정보

영어 이름Clusterin시판 약물 수0
임상 약물 수1표적 별명Epididymis Secretory Sperm Binding Protein,CLI,Apolipoprotein J,ApoJbeta,Complement cytolysis inhibitor a chain,Testosterone-repressed prostate message 2,Complement cytolysis inhibitor b chain,ApoJalpha,AAG4,Complement cytolysis inhibitor,NA1/NA2,APOJ,CLU,Clusterin,Complement-Associated Protein SP-40,40,Complement Lysis Inhibitor,Sulfated Glycoprotein 2,Ku70-Binding Protein 1,TRPM-2,KUB1,Clusterin (Complement Lysis Inhibitor, SP-40,40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, Apolipoprotein J),Aging-Associated Gene 4 Protein,Aging-Associated Protein 4,APO-J,SGP-2,SP-40,CLU1,CLU2,SGP2,TRPM2
최고 연구 개발 단계Phase 2 Clinical
영어 이름Clusterin
표적 별명Epididymis Secretory Sperm Binding Protein,CLI,Apolipoprotein J,ApoJbeta,Complement cytolysis inhibitor a chain,Testosterone-repressed prostate message 2,Complement cytolysis inhibitor b chain,ApoJalpha,AAG4,Complement cytolysis inhibitor,NA1/NA2,APOJ,CLU,Clusterin,Complement-Associated Protein SP-40,40,Complement Lysis Inhibitor,Sulfated Glycoprotein 2,Ku70-Binding Protein 1,TRPM-2,KUB1,Clusterin (Complement Lysis Inhibitor, SP-40,40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, Apolipoprotein J),Aging-Associated Gene 4 Protein,Aging-Associated Protein 4,APO-J,SGP-2,SP-40,CLU1,CLU2,SGP2,TRPM2
시판 약물 수0
임상 약물 수1
최고 연구 개발 단계Phase 2 Clinical

Clusterin 제품 목록

  • 속성

    Protein (2)

  • 제품 라이브러리

    온라인 (2)

  • Human (1)Hamster (1)

  • 태그

    His Tag (2)

  • 마커

    Unconjugated (2)

제품 번호발현 시스템제품 설명단백질 구조순도특성
Human
HEK293
Human Clusterin / CLUS Protein, His Tag
Hamster
CHO
Hamster Clusterin / CLUS Protein, His Tag
총 수량2
  • 1

Clusterin분자 배경

Clusterin (CLU/ApoJ)​ is a sticky, CHO-derived glycoprotein secreted as a ~75–80 kDa disulfide-linked heterodimer. Due to hydrophobic/glycan-mediated interactions, it often co-purifies with mAbs and persists through Protein A, posing risks to product stability. As a high-priority HCP, residual CLU requires targeted monitoring via orthogonal methods (LC-MS/MS or specific ELISA) alongside total HCP assays.

Clusterin분자 별명

CLU,Clusterin,AAG4,APOJ,CLI,KUB1,SGP-2,SP-40,TRPM2

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
SotevtamabAB-sCLU mAB; 16B5; AB-16B5Phase 2 ClinicalNational Research Council Biotechnology Research InstituteCarcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Neoplasm Metastasis; Solid tumours
상세
  • 분자 정보
  • 제품 목록
  • 임상 약물 정보
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