CLEC5A
CLEC5A 제품 목록
- 속성
Protein (3)
- 제품 라이브러리
온라인 (3)
- 종
Human (2)Mouse (1)
- 태그
His Tag (2)Fc Tag (1)
- 마커
Unconjugated (3)
| 제품 번호 | 종 | 발현 시스템 | 제품 설명 | 단백질 구조 | 순도 | 특성 |
|---|---|---|---|---|---|---|
 Human | HEK293 | Human CLEC5A / MDL-1 Protein, His Tag, active dimer, low endotoxin (MALS & SPR verified) |  |  | ||
| Human | HEK293 | Human CLEC5A / MDL-1 Protein, Fc Tag, low Endotoxin (MALS & SPR verified) |  | | | |
 Mouse | HEK293 | Mouse CLEC5A / MDL-1 Protein, His Tag (MALS & SPR verified) |  | | |
총 수량3
- 1
CLEC5A분자 배경
CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily.CLEC5A is expressed on monocytes, macrophages, and neutrophils. Its expression is up-regulated on monocytes in rheumatoid arthritis. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
- 제품 목록