언어 선택

Claudin-6

Claudin-6 분자 정보

영어 이름	Claudin 6	시판 약물 수	0
임상 약물 수	13	표적 별명	UNQ757/PRO1488，Claudin-6，CLDN6，Claudin 6，Skullin
최고 연구 개발 단계	Phase 2 Clinical

영어 이름	Claudin 6
표적 별명	UNQ757/PRO1488，Claudin-6，CLDN6，Claudin 6，Skullin
시판 약물 수	0
임상 약물 수	13
최고 연구 개발 단계	Phase 2 Clinical

Claudin-6 제품 목록

속성
Protein (10)Cell (1)
제품 라이브러리
온라인 (11)
종
Human (11)
태그
His Tag & Strep Tag (2)His Tag & Flag Tag & GFP Tag (2)GFP Tag (1)- (5)Flag Tag & His Tag & Strep Tag (1)
마커
Unconjugated (5)GFP Fusion (2)- (1)Biotin-labeled (3)

제품 번호	종	발현 시스템	제품 설명
HOT CHEK-ATP138	Human	HEK293	HEK293/Human Claudin-6 Stable Cell Line
HOT CL6-H5289	Human	InsectCells	Human Claudin-6 / CLDN6 Full Length Protein, His,Twin-Strep Tag (Detergent)
HOT CL6-H52P7	Human	HEK293	Human Claudin-6 / CLDN6 Full Length Protein (VLP)
CL6-H5286	Human	InsectCells	Human Claudin-6 / CLDN6 Full Length Protein, His,Twin-Strep Tag (Nanodisc)
CL6-H52D3	Human	HEK293	Human Claudin-6 Full Length Protein, Flag,His Tag&Twin-Strep Tag (Nanodisc-pro)
CL6-H52M3	Human	HEK293	Fluorescent Human Claudin-6 Full Length Protein, Flag,His Tag,GFP Tag (Nanodisc-pro)
CL6-H82P3	Human	HEK293	Biotinylated Human Claudin-6 / CLDN6 Full Length Protein (VLP)
CL6-H85D3	Human	InsectCells	Biotinylated Human Claudin-6 Full Length Protein, His,Avitag™&Flag Tag (Detergent)
CL6-H85D4	Human	InsectCells	Biotinylated Human Claudin-6 Full Length Protein, His,Avitag™&Flag Tag (Nanodisc)
CL6-HF2G8	Human	HEK293	Fluorescent Human Claudin-6 / CLDN6 Full Length Protein (VLP)

총 수량11

Claudin-6분자 배경

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Claudin-6, also knows as CLDN6, is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. And it is one of the entry cofactors for hepatitis C virus. The methylation of CLDN6 may be involved in esophageal tumorigenesis. The gene of CLDN6 is adjacent to another family member CLDN9 on chromosome 16.

Claudin-6분자 별명

Claudin-6,CLDN6

항체 프로젝트 거래 플랫폼

프로젝트 이름	프로젝트 단계	분자 유형	분자 출처	질병 영역	적응증
CLDN6 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Ovarian cancer,Lung adenocarcinoma

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
QLS-5132	QLS5132; QLS-5132	Phase 2 Clinical	Qilu Pharmaceutical Co Ltd	Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Ovarian Neoplasms; Solid tumours; Stomach Neoplasms	상세
TORL-1-23	TORL-1-23	Phase 2 Clinical	Torl Biotherapeutics LLC	Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Endometrial Neoplasms; Fallopian Tube Diseases; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Diseases; Peritoneal Neoplasms; Solid tumours	상세
PLB-002	PLB-002; PLB002	Phase 1 Clinical	PrimeLink BioTherapeutics	Endometrial Neoplasms; Ovarian Neoplasms; Solid tumours; Testicular Neoplasms	상세
BGB-B455	BGB-B455	Phase 1 Clinical	BeOne Medicines Ltd	Solid tumours	상세
AT03-65	AT-03-65; AT03-65	Phase 1 Clinical	Axcynsis Therapeutics Pte Ltd	Solid tumours	상세
ARC-101	ARC101; ARC-101	Phase 1 Clinical	Third Arc Bio Inc	Endometrial Neoplasms; Lung Neoplasms; Ovarian Neoplasms; Solid tumours	상세
CTIM-76	CTIM-76	Phase 1 Clinical	Integral Molecular Inc	Endometrial Neoplasms; Neoplasms; Ovarian Neoplasms; Solid tumours; Testicular Neoplasms	상세
NBL-028	NBL028; NBL-028	Phase 1 Clinical	Novarock Biotherapeutics Ltd, Shanghai Xinshi Biological Medicine Co Ltd	Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Neoplasms; Ovarian Neoplasms; Solid tumours; Stomach Neoplasms; Testicular Neoplasms	상세
XmAb-541	XmAb541; XmAb-541	Phase 1 Clinical	Xencor Inc	Endometrial Neoplasms; Germinoma; Neoplasms, Germ Cell and Embryonal; Ovarian germ cell tumor; Ovarian Neoplasms	상세
SAIL-66	SAIL66; SAIL-66	Phase 1 Clinical	Chugai Pharmaceutical Co Ltd	Solid tumours	상세
CLDN6-CAR-NK Cell Therapy		Phase 1 Clinical	Second Affiliated Hospital Of Guangzhou Medical University	Endometrial Neoplasms; Ovarian Neoplasms	상세
TJ-C64B	TJ-C64B	Phase 1 Clinical	I-Mab Biopharma Co Ltd	Ovarian Neoplasms; Stomach Neoplasms	상세
CLDN6 CAR-T cell therapy (BioNTech)	BNT-211	Phase 1 Clinical	Biontech Se	Germinoma; Neoplasms, Gonadal Tissue; Solid tumours; Testicular Neoplasms	상세