CEACAM-5

CEACAM-5

CEACAM-5 분자 정보

Molecule Name
Carcinoembryonic antigen related cell adhesion molecule 5
분자 별명
CEACAM-5,CD66e,CEA,Meconium antigen 100
Drug Development Progress
임상 약물 수18
시판 약물 수0
최고 연구 개발 단계Phase 3 Clinical
표적 별명
CEA Cell Adhesion Molecule 5,CEACAM5,Meconium antigen 100,CEA,Carcinoembryonic Antigen Related Cell Adhesion Molecule 5,Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5,Carcinoembryonic Antigen,CD66e Antigen,CD66e
분자 배경
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

CEACAM-5 제품 목록

Species
  • Human(13)
  • Cynomolgus(3)
  • Mouse(2)
  • Rhesus macaque(1)
Tag
  • His Tag(9)
  • His Tag & Avi Tag(4)
  • Fc Tag(3)
  • Llama IgG Fc Tag(2)
  • Fc Tag & Avi Tag(1)
Host
  • HEK293(19)
Conjugate
  • Unconjugated(12)
  • Biotin-labeled(5)
  • FITC Labeled(2)
Grade
  • RUO(18)
  • PG (pre-GMP)(1)
Low Endotoxin
  • Yes(4)
  • No(15)
You Have Viewed 1-10 Of 19 Results
  • 1
  • 2

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임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
Tusamitamab RavtansineSAR-408701; IBI-126Phase 3 ClinicalImmunogen Inc
Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Esophageal Neoplasms; Lung Neoplasms; Metastatic breast cancer; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms
상세
SGM-101SGM-101Phase 3 ClinicalSurgimab Sas
Brain Diseases; Brain metastases; Brain Neoplasms; Colonic Diseases; Colonic Neoplasms; Colorectal Neoplasms; Gastrointestinal Diseases; Gastrointestinal Neoplasms; Intestinal Diseases; Intestinal Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms
상세
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute)CVAC-301; CV-301Phase 2 ClinicalTherion Biologics
Adenocarcinoma; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Cystadenocarcinoma; Intestinal Neoplasms; Melanoma; Neoplasm Metastasis; Ovarian Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Solid tumours; Urinary Bladder Neoplasms
상세
NEO-201NEO-201Phase 2 ClinicalNational Cancer Institute, Precision Biologics Inc
Carcinoma, Non-Small-Cell Lung; Squamous Cell Carcinoma of Head and Neck; Uterine Cervical Neoplasms; Uterine Neoplasms
상세
Anti-CEA CAR T cell therapy (Shanghai GeneChem)Phase 2 ClinicalShanghai Genechem Co Ltd
Colorectal Neoplasms; Liver Neoplasms
상세
BMS-986490BMS-986490Phase 2 ClinicalBristol-Myers Squibb Company
Solid tumours
상세
LM-24C5LM-24C5Phase 2 ClinicalLaNova Medicines Ltd
Neoplasms; Solid tumours
상세
Precemtabart tocentecanM-9140; M9140Phase 2 ClinicalMerck KGaA, Darmstadt, Germany
Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms
상세
MFE-23-CD3z T cell therapy (Cancer Research Technology)Phase 1 ClinicalCancer Research Technology
Neoplasms
상세
anti-CEA CAR T-cell therapy (Shanghai First Song Therapeutics)Phase 1 ClinicalShanghai Simcere Pharmaceutical Co Ltd
Colorectal Neoplasms; Esophageal Neoplasms; Pancreatic Neoplasms; Small Intestine Cancers; Solid tumours; Stomach Neoplasms
상세
125-Iodine-labeled MFE-23Phase 1 ClinicalCancer Research UK
Neoplasms
상세
anti-CEA CAR-T cell therapy (Sorrento/TNK therapeutics/Roger Williams Medical Center)Phase 1 ClinicalBeth Israel Deaconess Medical Center
Adenocarcinoma; Liver Neoplasms; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours
상세
CEACAM5-TOPO1 ADC (Bristol-Myers Squibb Company)Phase 1 ClinicalBristol-Myers Squibb Company
Solid tumours
상세
124I-M5APhase 1 ClinicalCity Of Hope National Medical Center, National Cancer Institute
Colorectal Neoplasms
상세
IBI-3020IBI3020; IBI-3020Phase 1 ClinicalXinda Biomedical Technology (Hangzhou) Co Ltd
Neoplasm Metastasis; Solid tumours
상세
SGN-CEACAM5CPF-08046050; SGN-CEACAM5C; SAR445953; SAR-445953Phase 1 ClinicalSanofi, Seagen Inc
Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Gastroesophageal Junction Neoplasms; Small Cell Lung Carcinoma; Solid tumours; Stomach Neoplasms
상세
EBC-129EBC129; EBC-129Phase 1 ClinicalExperimental Drug Development Centre
Solid tumours
상세
GB-5012GB-5012ClinicalShanghai Genbase Biotechnology Co Ltd
Colonic Neoplasms
상세
Customer Reviews
  • n***l2026-08-21
    This protein was purchased for target testing. The product was very easy to reconstitute and produced accurate results. The shipping speed of the product was more efficient than estimated which was greatly appreciated. We enjoy ordering high quality products from Acro.