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CD8 alpha

CD8 alpha 분자 정보

영어 이름	Cluster of differentiation 8	시판 약물 수	0
임상 약물 수	18	표적 별명	CD8 Antigens
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Cluster of differentiation 8
표적 별명	CD8 Antigens
시판 약물 수	0
임상 약물 수	18
최고 연구 개발 단계	Phase 3 Clinical

CD8 alpha 제품 목록

속성
Protein (13)
제품 라이브러리
온라인 (13)
종
Mouse (3)Human (8)Cynomolgus (2)
태그
His Tag & Avi Tag (4)His Tag (8)Fc Tag (1)
마커
Biotin-labeled (3)Unconjugated (4)AF488 Labeled (3)AF647 Labeled (1)PE Labeled (1)APC Labeled (1)

제품 번호	종	발현 시스템	제품 설명
HOT CDA-H52H3	Human	HEK293	Human CD8 alpha / CD8A Protein, His Tag, low endotoxin (MALS verified)
HOT CDA-H82E3	Human	HEK293	Biotinylated Human CD8 alpha / CD8A Protein, His,Avitag™ (MALS verified)
HOT CDA-M82E8	Mouse	HEK293	Biotinylated Mouse CD8 alpha / CD8A Protein, His,Avitag™ (HPLC verified)
HOT CDA-C52H4	Cynomolgus	HEK293	Cynomolgus CD8 alpha / CD8A Protein, His Tag, low endotoxin (MALS verified)
CDA-H5258	Human	HEK293	Human CD8 alpha Protein, Fc Tag, low endotoxin (MALS verified)
CDA-HA2H4	Human	HEK293	Alexa Fluor™ 488-Labeled Human CD8 alpha Protein, His TagStar Staining
CDA-HA2H5	Human	HEK293	Alexa Fluor™ 647-Labeled Human CD8 alpha Protein, His TagStar Staining
CDA-HA2H6	Human	HEK293	Alexa Fluor™ 488-Labeled Human CD8 alpha Protein, His Tag
CDA-HA2H7	Human	HEK293	APC-Labeled Human CD8 alpha Protein, His TagStar Staining
CDA-HP2H3	Human	HEK293	PE-Labeled Human CD8 alpha Protein, His TagStar Staining

총 수량13

CD8 alpha분자 배경

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

CD8 alpha분자 별명

CD8A,CD8,Leu2,MAL,p32

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
89Zr-Df-crefmirlimab	IAB-22-M2C	Phase 3 Clinical	Imaginab Inc	Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Leukoencephalopathy, Progressive Multifocal; Lymphoma; Melanoma; Multiple Sclerosis; Skin Melanoma; Solid tumours	상세
RB-0003	RB-0003; BNT-111	Phase 2 Clinical	Biontech Se, Tron	Melanoma	상세
CD8+ memory T cell therapy (Stanford University)		Phase 2 Clinical	Stanford University	Leukemia; Leukemia, Myelogenous, Chronic; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma	상세
GEN-009	GEN-009	Phase 2 Clinical	Genocea Biosciences Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Skin Melanoma; Squamous Cell Carcinoma of Head and Neck	상세
VE-800	VE-800	Phase 2 Clinical	Vedanta Biosciences Inc	Colorectal Neoplasms; Gastroesophageal Junction Neoplasms; Melanoma; Neoplasm Metastasis; Stomach Neoplasms	상세
EBViNT Cell (Eutilex)		Phase 2 Clinical	Eutilex	Lymphoma, Extranodal NK-T-Cell	상세
ZED88082A	ZED88082A	Phase 2 Clinical	Umcg The University Medical Center Groningen	Neoplasm Metastasis; Neoplasms	상세
AZD-6750	AZD6750; AZD-6750	Phase 2 Clinical	Astrazeneca Plc	Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Cystadenocarcinoma, Serous; Melanoma; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms	상세
AZD-9793	AZD9793; AZD-9793	Phase 2 Clinical	Astrazeneca Plc	Carcinoma, Hepatocellular; Neoplasm Metastasis; Solid tumours	상세
AZD-5492	AZD5492	Phase 2 Clinical	Astrazeneca Plc	Arthritis, Rheumatoid; Leukemia, B-Cell; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Myositis; Neoplasms	상세
SNA-006	68-Ga-NODAGA-SNA-006; 68Ga-NODAGA-SNA006; SNA-006	Phase 2 Clinical	Smartnuclide Biopharma	Neoplasms; Solid tumours	상세
NY-ESO-1-specific autologous CD8+ T-cell therapy (Fred Hutchinson Cancer Research Center)		Phase 1 Clinical	Fred Hutchinson Cancer Research Center, National Cancer Institute	Liposarcoma; Sarcoma; Sarcoma, Synovial	상세
MTX-101 (Mozart Therapeutics)	MTX-101 (Mozart Therapeutics)	Phase 1 Clinical	Mozart Therapeutics Inc	Autoimmune Diseases; Diabetes Mellitus, Type 1	상세
[18F]GEH200521	GEH200521 (18F); GEH-200521	Phase 1 Clinical	Ge Healthcare	Solid tumours	상세
Tcrx T cell Therapy(Second Affiliated Hospital School Of Zhejiang University School Of Medicine)		Phase 1 Clinical	Second Affiliated Hospital School Of Zhejiang University School Of Medicine	Gastroesophageal Junction Neoplasms; Stomach Neoplasms	상세
SCRI-E2CAR_EGFRtv1	SCRI-E2CAR_EGFRtv1	Phase 1 Clinical	Umoja BioPharma Inc	Osteosarcoma	상세
89Zr-DFO-REGN5054	89Zr-DFO-REGN5054	Phase 1 Clinical	Regeneron Pharmaceuticals Inc	Solid tumours	상세
AGX-148	AGX-148; AGX148	Phase 1 Clinical	AgonOx Inc	Colorectal Neoplasms; Genital Neoplasms, Female; Lung Neoplasms; Melanoma; Neoplasms; Squamous Cell Carcinoma of Head and Neck; Urogenital Neoplasms	상세