CCR8

CCR8 분자 정보

영어 이름C-C chemokine receptor type 8시판 약물 수0
임상 약물 수21표적 별명Chemokine (C-C) Receptor 8,CC Chemokine Receptor 8,CDw198 Antigen,C-C CKR-8,CC-CKR-8,CCR-8,CMKBRL2,C-C Motif Chemokine Receptor 8,CC chemokine receptor CHEMR1,C-C chemokine receptor type 8,Chemokine (C-C Motif) Receptor 8,C-C Chemokine Receptor Type 8,CC Chemokine Receptor CHEMR1,Chemokine Receptor-Like 1,Chemokine (C-C) Receptor-Like 2,CC-Chemokine Receptor Chemr1,CD_antigen=CDw198,Chemokine receptor-like 1,CKRL1,CKR-L1,CMKBR8,GPRCY6,GPR-CY6,TER1,CDw198,CY6
최고 연구 개발 단계Phase 3 Clinical
영어 이름C-C chemokine receptor type 8
표적 별명Chemokine (C-C) Receptor 8,CC Chemokine Receptor 8,CDw198 Antigen,C-C CKR-8,CC-CKR-8,CCR-8,CMKBRL2,C-C Motif Chemokine Receptor 8,CC chemokine receptor CHEMR1,C-C chemokine receptor type 8,Chemokine (C-C Motif) Receptor 8,C-C Chemokine Receptor Type 8,CC Chemokine Receptor CHEMR1,Chemokine Receptor-Like 1,Chemokine (C-C) Receptor-Like 2,CC-Chemokine Receptor Chemr1,CD_antigen=CDw198,Chemokine receptor-like 1,CKRL1,CKR-L1,CMKBR8,GPRCY6,GPR-CY6,TER1,CDw198,CY6
시판 약물 수0
임상 약물 수21
최고 연구 개발 단계Phase 3 Clinical

CCR8 제품 목록

  • 속성

    Protein (8)Cell (1)Antibody (1)

  • 제품 라이브러리

    온라인 (10)

  • Human (7)Mouse (2)Rhesus macaque (1)

  • 태그

    His Tag & Flag Tag (1)- (7)His Tag & Flag Tag & Strep Tag (2)

  • 마커

    Unconjugated (7)- (1)Biotin-labeled (2)

CCR8분자 배경

This entry represents CC chemokine receptor 8 (CCR8), which it is expressed predominantly in lymphoid tissues and has also been found in glomerular podocytes and human umbilical vein endothelial cells (HUVECs). CCR8 is associated with Th2 lymphocytes, which are critical for allergy, and has a role in lymphocyte activation, migration, proliferation and differentiation and in allergic diseases. CCR8 binds to CCL1 (also known as I-309) and to CCL16 (also known as liver expressed chemokine). It also exhibits a high affinity for three chemokines of viral origin: vMIP-I, vMIP-II and vMCC-I.

CCR8분자 별명

CC chemokine receptor 8,CDw198,ChemR1,CKRL1,CKR-L1,CKRL1,CY6,GPRCL1,GPRCY6,GPR-CY6,TER-1

항체 프로젝트 거래 플랫폼

프로젝트 이름프로젝트 단계분자 유형분자 출처질병 영역적응증
CCR8 mAb - 01PCCMonoclonalHumanized MouseSolid TumorSolid tumor
CCR8 mAb - 02LeadMonoclonalHumanized MouseSolid TumorSolid tumor
CCR8 mAb - 03PCCMonoclonalHumanized MouseSolid TumorSolid tumor

라이선싱 협력

프로젝트 이름약물 유형치료 영역적응증단계권리 지역
CCR8 Humanized AntibodyBispecific antibodyOncology/CancerSolid TumorPreclinicalGlobal

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
CafelkibartLM-108Phase 3 ClinicalLaNova Medicines LtdCarcinoma, Non-Small-Cell Lung; Gastroesophageal Junction Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms; Triple Negative Breast Neoplasms
상세
ImzokitugBMS-986340; ONO-7427Phase 2 ClinicalEeig Bristol-Myers Squibb Manufacturing Company Bristol-Myers Squibb SrlCarcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Esophageal Neoplasms; Melanoma; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms
상세
TAK- 188TAK- 188Phase 2 ClinicalTakeda Pharmaceutical Co LtdSolid tumours
상세
QLP2117QLP2117; QLP-2117Phase 2 ClinicalQilu Pharmaceutical Co LtdNeoplasms; Solid tumours
상세
DT-7012DT-7012Phase 2 ClinicalDomain Therapeutics SALymphoma, T-Cell, Cutaneous; Mycosis Fungoides; Neoplasms; Sezary Syndrome; Solid tumours
상세
S-531011S-531011Phase 2 ClinicalShionogi IncSolid tumours
상세
IPG-7236IPG-7236Phase 2 ClinicalNanjing Immunophage Biotech Co LtdBreast Neoplasms; Dermatitis, Atopic; Solid tumours
상세
anti-CCR8 antibody (Bristol-Myers Squibb)Phase 1 ClinicalBristol-Myers Squibb CompanySolid tumours
상세
PSB-114PSB-114Phase 1 ClinicalQilu Puget Sound Biotherapeutics CorpNeoplasms
상세
BAY-3375968BAY-3375968Phase 1 ClinicalBayer AGNeoplasms; Solid tumours
상세
ICP-B05ICPB05; CM-369Phase 1 ClinicalInnoCare Pharma Ltd, Keymed Biosciences Co LtdHematologic Neoplasms; Solid tumours
상세
HBM-1022HBM-1022Phase 1 ClinicalHarbour BiomedNeoplasms
상세
DenikitugJTX-1811; GS-1811Phase 1 ClinicalJounce Therapeutics IncSolid tumours
상세
TagmokitugCHS-114; SRF-114Phase 1 ClinicalSurface Oncology IncNeoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck
상세
TQB-6457TQB-6457; TQB6457Phase 1 ClinicalShanghai Chia Tai Tianqing Pharmaceutical Technology Development Co LtdNeoplasms
상세
KYS-2301KYS2301; KYS-2301Phase 1 ClinicalJiangsu Kanion Pharmaceutical Co LtdDermatitis, Atopic
상세
AMG-355AMG 355; AMG-355Phase 1 ClinicalAmgen IncSolid tumours
상세
HC-006HC-006; HC006Phase 1 ClinicalShanghai Hongcheng Pharmaceutical Co LtdNeoplasms; Solid tumours
상세
BGB-A3055BGB-A3055Phase 1 ClinicalBeOne Medicines LtdSolid tumours
상세
ABBV-514ABBV-514Phase 1 ClinicalAbbvie IncCarcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Cystadenocarcinoma, Serous; Ovarian Neoplasms; Pancreatic Neoplasms; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms
상세
IPGA-05IPGA-05; IPG0521; IPG-0521Phase 1 ClinicalNanjing Immunophage Biotech Co LtdAutoimmune Diseases; Immunoglobulin G4-Related Disease; Solid tumours
상세
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