CCL3 분자 정보
Molecule Name
Macrophage inflammatory protein 1-α
분자 별명
C-C motif chemokine 3,MIP1-(a),AI323804,CCL3,chemokine (C-C motif) ligand 3,G0S19-1,LD78a,LD78alpha,MIP1 alpha,MIP-1 alpha,MIP1A,MIP-1alpha,MIP1-alpha
Drug Development Progress
임상 약물 수0
시판 약물 수0
최고 연구 개발 단계Preclinical
표적 별명
CCL3，PAT 464.1，C-C Motif Chemokine 3，Macrophage inflammatory protein 1-alpha，G0S19-1，C-C Motif Chemokine Ligand 3，Small Inducible Cytokine A3 (Homologous To Mouse Mip-1a)，Tonsillar Lymphocyte LD78 Alpha Protein，Chemokine (C-C Motif) Ligand 3，MIP-1-Alpha，SIS-Beta，LD78ALPHA，Chemokine CCL3，G0/G1 switch regulatory protein 19-1，Small-inducible cytokine A3，SCYA3，LD78-alpha(4-69)，MIP1A
분자 배경
CCL3, also know as MIP-1-alpha, is monokine with inflammatory and chemokinetic properties. CCL3 is an important chemokine implicated in both immune surveillance and tolerance, has emerged as a prognostic biomarker in both solid and hematological malignancies. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
CCL3 제품 목록
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