언어 선택

CA125

CA125 분자 정보

영어 이름	Mucin-16	시판 약물 수	0
임상 약물 수	11	표적 별명	Mucin-16 Short Isoform，Mucin-16 Long Isoform，Ovarian carcinoma antigen CA125，Ovarian cancer-related tumor marker CA125，MUC16，MUC-16，CA-125，Mucin 16， Cell Surface Associated，CA125，CA125 Ovarian Cancer Antigen，Mucin-16，CA-125 Antigen，FLJ14303
최고 연구 개발 단계	Phase 3 Clinical

영어 이름	Mucin-16
표적 별명	Mucin-16 Short Isoform，Mucin-16 Long Isoform，Ovarian carcinoma antigen CA125，Ovarian cancer-related tumor marker CA125，MUC16，MUC-16，CA-125，Mucin 16， Cell Surface Associated，CA125，CA125 Ovarian Cancer Antigen，Mucin-16，CA-125 Antigen，FLJ14303
시판 약물 수	0
임상 약물 수	11
최고 연구 개발 단계	Phase 3 Clinical

CA125 제품 목록

속성
Protein (8)
제품 라이브러리
온라인 (8)
종
Human (3)Cynomolgus (2)Mouse (1)Rabbit (1)Rat (1)
태그
Fc Tag & Avi Tag (2)His Tag (5)His Tag & Avi Tag (1)
마커
Biotin-labeled (3)Unconjugated (5)

제품 번호	종	발현 시스템	제품 설명
HOT CA5-H52H6	Human	HEK293	Human CA125 / MUC16 (13810-14451) Protein, His Tag, low endotoxin (MALS verified)
HOT CA5-H82F4	Human	HEK293	Biotinylated Human CA125 / MUC16 Protein, Fc,Avitag™
HOT CA5-H82F8	Human	HEK293	Biotinylated Human CA125 / MUC16 (13810-14451) Protein, Fc,Avitag™
CA5-M52H6	Mouse	HEK293	Mouse CA125 / MUC16 Protein, His Tag (MALS verified)
CA5-C52H8	Cynomolgus	HEK293	Cynomolgus CA125 / MUC16 Protein, His Tag, low endotoxin (MALS verified)
CA5-C82E9	Cynomolgus	HEK293	Biotinylated Cynomolgus CA125 / MUC16 Protein, His,Avitag™ (MALS verified)
CA5-R52H4	Rabbit	HEK293	Rabbit CA125 / MUC16 Protein, His Tag
CA5-R52H5	Rat	HEK293	Rat CA125 Protein, His Tag (MALS verified)

총 수량8

CA125분자 배경

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

CA125분자 별명

CA125,CA-125,CA125MUC-16,FLJ14303,MUC16,mucin 16,mucin-16

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Oregovomab	B43.13	Phase 3 Clinical	Paladin Pharma	Abdominal Neoplasms; Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms	상세
EB-NK-FM (FRalpha/MUC16)	EB-NK-FM	Phase 2 Clinical	Beijing Biotech	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	상세
EB-NK-MM (MSLN/MUC16)	EB-NK-MM	Phase 2 Clinical	Beijing Biotech	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	상세
LBL-033	LBL-033	Phase 2 Clinical	Nanjing Leadsbiolabs Co Ltd	Neoplasms	상세
REGN-5668	REGN-5668	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Endometrial Neoplasms; Fallopian Tube Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	상세
Ubamatamab	REGN-4018	Phase 2 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Fallopian Tube Neoplasms; Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms	상세
PRGN-3005	PRGN-3005	Phase 1 Clinical	Precigen Inc	Esophageal Neoplasms; Fallopian Tube Neoplasms; Lymphoma, Non-Hodgkin; Ovarian Neoplasms; Peritoneal Neoplasms; Sarcoma; Uterine Cervical Neoplasms	상세
GB-5267	GB-5267	Phase 1 Clinical	Generate Biomedicines Inc	Ovarian Neoplasms	상세
HWK-016	HWK-016	Phase 1 Clinical	Wuxi Biologics Co Ltd	Endometrial Neoplasms; Ovarian Neoplasms; Uterine Cervical Neoplasms	상세
JCAR-020	JCAR-020	Phase 1 Clinical	Eureka Therapeutics Inc, Juno Therapeutics Inc, Memorial Sloan Kettering Cancer Center	Solid tumours	상세
Mucin-16 (MUC16) Protein Targeting Immune Cell Therapy(Regeneron Pharmaceutical)	27T-51; 27T51	Phase 1 Clinical	Regeneron Pharmaceuticals Inc	Carcinoma, Ovarian Epithelial; Fallopian Tube Neoplasms; Peritoneal Neoplasms	상세

제품 리뷰

E***e2025-08-07
0사람들이 좋아합니다
Human CA125 / MUC16 (13810-14451) Protein, His Tag, low endotoxin (MALS verified)
We used Acro Biosystems' recombinant Human CA125 / MUC16 protein (Catalog #CA5-H52H6) as a target antigen for antibody screening and downstream validation. The protein was employed in both ELISA and FACS assays. In ELISA, we observed strong, dose-dependent binding with minimal background, which enabled clear differentiation of candidate clones. For FACS, we used the protein to confirm surface staining specificity on engineered cell lines, and the results were consistent and reproducible. I was particularly impressed with the proteins high purity.