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beta-Glucuronidase/GUSB

beta-Glucuronidase/GUSB Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
BEB-H52H3	Human	HEK293	Human beta-Glucuronidase/GUSB Protein, His Tag (active enzyme)

Total: 1

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beta-Glucuronidase/GUSB Background

Human beta -Glucuronidase (EC 3.2.1.31) encoded by the GUSB gene is a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans that include heparan sulfate, chondroitin sulfate and hyaluronan. The enzyme is only active on the glucuronic acid of the non-reducing end. The native protein has been reported as a tetrameric glycoprotein composed of identical subunits.

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
HBM-1020	R-1020; HBM-1020	Phase 1 Clinical	Harbour Biomed	Solid tumours	Details
NPX-887	NPX887; NPX-887	Phase 1 Clinical	NextPoint Therapeutics Inc	Solid tumours; Neoplasms	Details
NPX-267	NPX-267	Phase 1 Clinical	NextPoint Therapeutics Inc	Neoplasms	Details