언어 선택

B21R

제품 문의

B21R분자 배경

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The cases are mostly in central and western Africa. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. The important target protein B21R with key immune dominant epitopes is considered to be the focus of monkeypox virus research.

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
BLU-782	BLU-782; IPN-60130	Phase 2 Clinical	Blueprint Medicines Corp, Ipsen SA	Myositis Ossificans	상세
Zilurgisertib	INCB-000928; INCB-00928	Phase 2 Clinical	Incyte Corp	Anemia; Polycythemia Vera; Myelodysplastic Syndromes; Kidney Diseases; Ossification, Heterotopic; Multiple Myeloma; Myositis Ossificans; Primary Myelofibrosis; Thrombocythemia, Essential	상세
KER-047	KER-047	Phase 1 Clinical	National Center For Advancing Translational Sciences	Anemia, Iron-Deficiency; Myositis Ossificans	상세
Itacnosertib	TP-0184	Phase 1 Clinical	Tolero Pharmaceuticals Inc, Sumitomo Dainippon	Solid tumours; Anemia	상세
BCX-9250	BCX-9250	Phase 1 Clinical	Biocryst Pharmaceuticals Inc	Myositis Ossificans	상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Momelotinib Dihydrochloride	CYT-387; GS-0387; GSK-3070785	Approved		Ojjaara, Omjjara	United States	Primary Myelofibrosis; Anemia	Glaxosmithkline Llc, Glaxosmithkline Plc	2023-09-15	Polycythemia; Polycythemia Vera; Anemia; Neoplasms; Myeloproliferative Disorders; Pancreatic Intraductal Neoplasms; Primary Myelofibrosis; Carcinoma, Pancreatic Ductal; Splenomegaly; Thrombocythemia, Essential; Carcinoma, Non-Small-Cell Lung	상세