Amphiregulin

Amphiregulin 분자 정보

영어 이름Amphiregulin시판 약물 수0
임상 약물 수2표적 별명AREGB,Colorectum cell-derived growth factor,AR,Schwannoma-Derived Growth Factor,Amphiregulin B,CRDGF,SDGF,SDGF GN
최고 연구 개발 단계Phase 1 Clinical
영어 이름Amphiregulin
표적 별명AREGB,Colorectum cell-derived growth factor,AR,Schwannoma-Derived Growth Factor,Amphiregulin B,CRDGF,SDGF,SDGF GN
시판 약물 수0
임상 약물 수2
최고 연구 개발 단계Phase 1 Clinical

Amphiregulin 제품 목록

  • 속성

    Protein (2)

  • 제품 라이브러리

    온라인 (2)

  • Human (2)

  • 태그

    His Tag & Avi Tag (2)

  • 마커

    Biotin-labeled (2)

제품 번호발현 시스템제품 설명단백질 구조순도특성
Human
HEK293
Biotinylated Human Amphiregulin Protein, His,Avitag™
Human
HEK293
Biotinylated Human Amphiregulin Protein, His,Avitag™ (HPLC verified)
총 수량2
  • 1

Amphiregulin분자 배경

Amphiregulin (AREG), which acts as one of the ligands for epidermal receptor growth factor receptor (EGFR), plays a crucial role in tissue repair, inflammation, and immunity. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]

Amphiregulin분자 별명

AR, AREGB, CRDGF, SDGF

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
SRN-001SRN-001Phase 1 ClinicalsiRNAgen Therapeutics IncMetabolic Dysfunction-Associated Steatotic Liver Disease; Idiopathic Pulmonary Fibrosis; Chronic Kidney Disease-Mineral and Bone Disorder
상세
PMG-1015PMG-1015Phase 1 ClinicalPulmongene LtdIdiopathic Pulmonary Fibrosis
상세
  • 분자 정보
  • 제품 목록
  • 임상 약물 정보
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