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Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Zanzalintinib	XL-092	Phase 3 Clinical	Exelixis Inc	Solid tumours; Leiomyosarcoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Carcinoma, Transitional Cell; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular	Details
KC1036	KC1036; KC-1036	Phase 3 Clinical	Beijing Konruns Pharmaceutical Co Ltd	Hematologic Neoplasms; Solid tumours; Digestive System Neoplasms; Sarcoma, Ewing; Thymus Neoplasms; Esophageal Squamous Cell Carcinoma; Adenocarcinoma; Neoplasm Metastasis	Details
Sitravatinib	MGCD-516; IND-155305; MGCD-0516; MG-91516; MG-516	Phase 3 Clinical		Breast Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Endometrial Neoplasms; Lung Neoplasms; Metastatic breast cancer; Esophageal Squamous Cell Carcinoma; Mouth Neoplasms; Carcinoma, Squamous Cell; Hepatic Insufficiency; Ureteral Neoplasms; Solid tumours; Lung Diseases; Liposarcoma; Uveal melanoma; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Carcinoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Kidney Neoplasms; Biliary Tract Neoplasms	Details
Ningetinib Tosylate	CT-053-PTSA; CT-053	Phase 2 Clinical	Hec Pharm Co Ltd	Intestinal Neoplasms; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Mecbotamab vedotin	BA-3011; BA3011; BA 3011	Phase 2 Clinical	Bioatla	Ovarian Neoplasms; Sarcoma, Synovial; Liposarcoma; Osteosarcoma; Sarcoma, Ewing; Sarcoma; Carcinoma, Non-Small-Cell Lung	Details
Merestinib	5OGS5K699E; LY-2801653	Phase 2 Clinical	Eli Lilly And Company	Biliary Tract Neoplasms; Skin Melanoma; Bone metastases; Solid tumours; Neoplasms; Pancreatic Neoplasms; Microsatellite instability-high cancer; Lymphoma, Mantle-Cell; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung	Details
ONO-7475	ONO-7475	Phase 2 Clinical	Ono Pharmaceutical Co Ltd	Leukemia; Solid tumours; Myelodysplastic Syndromes; Leukemia, Myeloid, Acute	Details
Bemcentinib	BGB-324; R-428	Phase 2 Clinical	Rigel Pharmaceuticals Inc	Coronavirus Disease 2019 (COVID-19); Glioblastoma; Pancreatic Neoplasms; Triple Negative Breast Neoplasms; Myelodysplastic Syndromes; Adenocarcinoma of Lung; Inflammatory Breast Neoplasms; Mesothelioma; Central Nervous System Neoplasms; Brain Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma	Details
Glesatinib	MGCD-265; MG-90265X; 7Q29OXD98N; MG-90265H9; MG-90265gly; MG-90265	Phase 2 Clinical		Neoplasms; Carcinoma, Non-Small-Cell Lung	Details
Enapotamab vedotin	AXL-107-MMAE	Phase 2 Clinical	Genmab A/S	Ovarian Neoplasms; Solid tumours; Neoplasms; Sarcoma; Thyroid Neoplasms; Endometrial Neoplasms; Carcinoma, Non-Small-Cell Lung; Melanoma; Uterine Cervical Neoplasms	Details
CCT301-38	CCT301-38; CCT301-38 AXL	Phase 2 Clinical	F1 Oncology, Bioatla	Carcinoma, Renal Cell; Rhinitis, Allergic, Seasonal	Details
XZB-0004	XZB-0004; SLC-0211; SLC-391	Phase 2 Clinical	Xuanzhu (Shijiazhuang) Biotechnology Co Ltd	Solid tumours; Hematologic Neoplasms; Myelodysplastic Syndromes; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Foodborne Diseases	Details
Butylidenephthalide	BDPH; HK-001; NSC-325307; LF-001 (Everfront Biotech)	Phase 2 Clinical	Everfront Biotech Co Ltd	Glioma; Amyotrophic Lateral Sclerosis	Details
Adrixetinib	Q-702	Phase 2 Clinical	Vichem Chemie, Max Planck Institute of Biochemistry, Lead Discovery Center GmbH	Erdheim-Chester Disease; Uterine Cervical Neoplasms; Central Nervous System Lymphoma; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Metastasis; Carcinoma, Hepatocellular; Lymphoma; Lymphoma, T-Cell, Cutaneous; Waldenstrom Macroglobulinemia; Leukemia, Myeloid, Acute; Primary Myelofibrosis; Histiocytic Sarcoma; Lymphoma, T-Cell, Peripheral; Histiocytosis, Langerhans-Cell; Lymphoma, Follicular; Histiocytosis, Sinus; Neoplasms; Myelodysplastic Syndromes; Leukemia, Myelomonocytic, Chronic; Esophageal Neoplasms; Leukemia, Lymphoid; Stomach Neoplasms; Solid tumours; Hematologic Neoplasms	Details
Dubermatinib	TP-0903	Phase 1 Clinical	Sumitomo Dainippon	Ovarian Neoplasms; Solid tumours; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Leukemia, Lymphocytic, Chronic, B-Cell; Melanoma; Carcinoma, Non-Small-Cell Lung	Details
INCB-081776	INCB-81776; INCB-081776	Phase 1 Clinical	Incyte Corp	Solid tumours; Squamous Cell Carcinoma of Head and Neck	Details
BPI-9016	BPI-9016; BPI-9016M	Phase 1 Clinical	Betta Pharmaceuticals Co Ltd	Solid tumours; Carcinoma, Non-Small-Cell Lung	Details
Mipasetamab uzoptirine	ADCT-601; BGB-601	Phase 1 Clinical	Adc Therapeutics Sa	Solid tumours	Details
NTQ-2494	NTQ2494; NTQ-2494	Phase 1 Clinical		Solid tumours; Hematologic Neoplasms; Leukemia, Myeloid, Acute	Details
CTS-2016	CTS-2016	Phase 1 Clinical		Myelodysplastic Syndromes; Leukemia, Myeloid, Acute	Details
AB-801	AB-801	Phase 1 Clinical	Arcus Biosciences Inc	Neoplasms	Details
FC-084-CSA	FC084CSA; FC-084-CSA	Phase 1 Clinical	FindCure Biosciences (ZhongShan) Co Ltd	Solid tumours	Details
NP-107	NP107; NP-107	Phase 1 Clinical	Shanghai Nawei Biotechnology Co Ltd	Solid tumours	Details
TT-00973	TT-00973	Phase 1 Clinical	TransThera Sciences (Nanjing) Inc	Solid tumours	Details
AGX-0073	AGX-0073	Phase 1 Clinical	Shanghai Aojian Biological Technology Co Ltd	Solid tumours	Details
PF-07265807	PF-07265807	Phase 1 Clinical	Pfizer Inc	Solid tumours; Neoplasm Metastasis	Details
NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology)	NP-01	Phase 1 Clinical	Shijiazhuang No 4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co Ltd	Solid tumours; Liver Neoplasms; Stomach Neoplasms; Lung Neoplasms	Details
cancer therapeutics (BerGenBio)	BGB-101; BGB-109; BGB-003; BGB-001	Phase 1 Clinical	Bergenbio		Details
NPS-1034	HOPE-777; KDDF-201111-02		Neopharma Ltd		Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Gilteritinib Fumarate	ASP-2215 hemifumarate; ASP-2215; 66D-92MGC8M (UNII code)	Approved	Astellas Pharma Inc	Xospata	Japan	Leukemia, Myeloid, Acute	Astellas Pharma Inc	2018-09-21	Solid tumours; Renal Insufficiency; Hepatic Insufficiency; Lung Neoplasms; Leukemia, Myeloid, Acute; Carcinoma, Non-Small-Cell Lung	Details
Cabozantinib S-malate	XL-184; BMS-907351; RO7047650; RO-7047650	Approved	Exelixis Inc	Cometriq, Cabometyx	United States	Thyroid Neoplasms; Carcinoma, Neuroendocrine	Exelixis Inc	2012-11-29	Neuroblastoma; Thyroid Neoplasms; Hepatic Insufficiency; Astrocytoma; Peritoneal Neoplasms; Bile Duct Neoplasms; Colorectal Neoplasms; Gliosarcoma; Urethral Neoplasms; Sarcoma, Clear Cell; Uterine Neoplasms; Cholangiocarcinoma; Neurofibroma, Plexiform; Brain Neoplasms; Adenocarcinoma, Clear Cell; Carcinoma, Adenosquamous; Medullary thyroid cancer (MTC); Sarcoma, Ewing; Sarcoma; Osteosarcoma; Sarcoma, Alveolar Soft Part; Neoplasm Metastasis; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Endometrioid; Thyroid Cancer, Papillary; Meningioma; Paraganglioma; Neoplasms, Germ Cell and Embryonal; Carcinoma, Hepatocellular; Prostatic Neoplasms; Glioma; Brain metastases; Endometrial Neoplasms; Leukemia, Myeloid, Acute; Carcinoma, Squamous Cell; Lymphoma; Carcinoma, Neuroendocrine; Fallopian Tube Neoplasms; Carcinoma, Renal Cell; Adenoma, Islet Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Renal Insufficiency; Hepatoblastoma; Pheochromocytoma; Carcinoid Tumor; Carcinoma, Merkel Cell; Rejection of liver transp	Details