Activin RIIA
Activin RIIA 분자 정보
| 영어 이름 | Activin receptor type-2A | 시판 약물 수 | 0 |
| 임상 약물 수 | 4 | 표적 별명 | Activin receptor type IIA，ACTR-IIA，ACTRIIA，ACVR2 |
| 최고 연구 개발 단계 | Phase 2 Clinical | ||
| 영어 이름 | Activin receptor type-2A |
| 표적 별명 | Activin receptor type IIA，ACTR-IIA，ACTRIIA，ACVR2 |
| 시판 약물 수 | 0 |
| 임상 약물 수 | 4 |
| 최고 연구 개발 단계 | Phase 2 Clinical |
Activin RIIA 제품 목록
- 속성
Protein (7)
- 제품 라이브러리
온라인 (7)
- 종
Human / Cynomolgus (4)Mouse (2)Rabbit (1)
- 태그
Fc Tag (1)His Tag & Avi Tag (2)His Tag (3)Fc Tag & Avi Tag (1)
- 마커
Unconjugated (4)Biotin-labeled (3)
| 제품 번호 | 종 | 발현 시스템 | 제품 설명 | 단백질 구조 | 순도 | 특성 |
|---|---|---|---|---|---|---|
 Mouse | HEK293 | Mouse Activin RIIA / ACVR2A Protein, His Tag, low endotoxin (SPR & HPLC verified) |  |  |  | |
| Mouse | HEK293 | Biotinylated Mouse Activin RIIA Protein, His,Avitag™ (MALS verified) |  | | | |
Human / Cynomolgus | HEK293 | Human / Cynomolgus Activin RIIA / ACVR2A Protein, His Tag, low endotoxin (MALS & SPR verified) |  | | | |
Human / Cynomolgus | HEK293 | Human / Cynomolgus Activin RIIA / ACVR2A Protein, Fc Tag |  | | | |
Human / Cynomolgus | HEK293 | Biotinylated Human / Cynomolgus Activin RIIA Protein, Avitag™,Fc Tag (MALS verified) |  | | | |
Human / Cynomolgus | HEK293 | Biotinylated Human / Cynomolgus Activin RIIA Protein, His,Avitag™ |  | | | |
 Rabbit | HEK293 | Rabbit Activin RIIA / ACVR2A Protein, His Tag (MALS verified) |  | | |
총 수량7
- 1
Activin RIIA분자 배경
Activin receptor type-2A (ACVR2A) is also known as activin receptor type IIA, ACTR-IIA, ACTRIIA, and ACVR2, and is a single-pass type I membrane protein. ACVR2A belongs to the protein kinase superfamily, the TKL Ser/Thr protein kinase family, and the TGFB receptor subfamily. Upon ligand binding, ACVR2A forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors, which then phosphorylate and activate SMAD transcriptional regulators. ACVR2A also serves as a receptor for activin A, activin B, and inhibin A (the latter in complex with betaglycan). Two type II activin receptors (ACVR2A and ACVR2B) have been identified, which bind different activins with distinct affinities.
Activin RIIA분자 별명
Activin receptor type IIA,ACTRIIA
임상 약물 정보
| 영어 이름 | 연구 코드 | 연구 개발 단계 | 회사 | 적응증 | 임상 시험 |
|---|---|---|---|---|---|
| LAE-102 | LAE-102 | Phase 2 Clinical | Laekna Therapeutics Shanghai Co Ltd | Carcinoma, Non-Small-Cell Lung; Metabolic Dysfunction-Associated Steatotic Liver Disease; Obesity; Overweight; Solid tumours | 상세 |
| SSS-67 | SSS67; SSS-67 | Phase 1 Clinical | Shenyang Sunshine Pharmaceutical Co Ltd | Obesity; Overweight | 상세 |
| JMT-206 | JMT206; JMT-206 | Phase 1 Clinical | Shanghai Jmt-Bio Inc | Body Weight; Obesity; Overweight; Sarcopenia | 상세 |
| IMC-003(ImmuneOnco Biopharmaceuticals) | IMM72; IMM-72; IMC-003; IMC-003(ImmuneOnco Biopharmaceuticals) | Phase 1 Clinical | Pulmonary Arterial Hypertension | 상세 |
제품 리뷰
L***i2024-11-05
1사람들이 좋아합니다We have been purchasing Activin products from Acro for a few years now and have always appreciated the quality and consistency. We were excited to see that biotinylated options are now available, as they fit our research needs perfectly. Acro's reliable service keeps us coming back as satisfied customers, and we look forward to using these new products.- A***z2022-06-15 0사람들이 좋아합니다The product quality was excellent. The technical services was better than all competitors and the logistics speed was very fast. All in all, a fantastic product and a fantastic company.
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