언어 선택

5-HT2AR

5-HT2AR 제품 목록

속성
Protein (2)
제품 라이브러리
온라인 (2)
종
Human (2)
태그
His Tag & Flag Tag (2)
마커
Unconjugated (2)

제품 번호	종	발현 시스템	제품 설명	단백질 구조	순도	특성
5HR-H55D3	Human	InsectCells	Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag (Detergent)
5HR-H55D4	Human	InsectCells	Human 5-HT2AR Protein (S162K, M164W, S372N), Flag,His Tag (Nanodisc-pro)

총 수량2

5-HT2AR분자 배경

This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

임상 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	적응증	임상 시험
Buntanetap	ANVS-405; ANVS-401	Phase 3 Clinical	Raptor Pharmaceutical	Down Syndrome; Chronic Traumatic Encephalopathy; Alzheimer Disease; Parkinson Disease; Cognitive Dysfunction; Frontotemporal Dementia	상세
Gantenerumab	MAb-31; R-1450; RG-1450; R-04909832	Phase 3 Clinical	Chugai Pharmaceutical Co Ltd	Alzheimer Disease; Dementia	상세
Valiltramiprosate	NRM-8499; ALZ-801; BLU-8499	Phase 3 Clinical	Alzheon Inc	Alzheimer Disease	상세
Solanezumab	LY-2062430	Phase 3 Clinical	Eli Lilly And Company	Alzheimer Disease; Dementia; Cognition Disorders	상세
Birtamimab	NEOD-001	Phase 3 Clinical	Prothena	Immunoglobulin Light-chain Amyloidosis; Amyloidosis	상세
Remternetug	LY-3372993	Phase 3 Clinical	Eli Lilly And Company	Alzheimer Disease; Dementia	상세
L-clausenamide		Phase 2 Clinical	Guangzhou Nuohao Pharmaceutical Technology Co Ltd, Institue Of Materia Medica Chinese Academy Of Medical Science, Qingdao Huanghai Pharmaceutical Co Ltd	Dementia; Cognitive Dysfunction; Memory Disorders	상세
Crenezumab	MABT-5102-A; RG-7412; R-7412; RO-5490245	Phase 2 Clinical	Ac Immune Sa	Alzheimer Disease	상세
11C-BF-227	11C-BF-227; [11C]BF-227	Phase 2 Clinical	Tohoku University	Diagnostic agents	상세
Pittsburgh Compound B	[11C]PIB; [11C]6-OH-BTA-1; 11C-PIB	Phase 2 Clinical	The University Of Utah, University Of Pittsburgh, Ge Healthcare, Uppsala Universitet	Ovarian Neoplasms; Brain Concussion; Breast Neoplasms; Alzheimer Disease; Alcoholism; Dementia; Parkinson Disease	상세
CT-1812	CT-1812; SV-119	Phase 2 Clinical	Cogrx	Alzheimer Disease; Cognitive Dysfunction; Lewy Body Disease; Macular Degeneration	상세
[18F]THK-5105	[18F]THK-5105	Phase 2 Clinical	Tohoku University	Alzheimer Disease	상세
Edonerpic	T-817 MA	Phase 2 Clinical	Toyama Chemical Co Ltd, Fujifilm Group	Alzheimer Disease; Cognitive Dysfunction; Hepatic Insufficiency	상세
ABvac-40	ABvac-40	Phase 2 Clinical	Araclon Biotech Sl	Alzheimer Disease; Cognitive Dysfunction	상세
PK-051	PK051; PK-051	Phase 2 Clinical	PharmaKure Ltd	Alzheimer Disease; Cognitive Dysfunction	상세
PRI-002	RD-2; PRI-002	Phase 2 Clinical	PRInnovation GmbH, Priavoid	Alzheimer Disease; Cognitive Dysfunction	상세
18F-92	18F-92	Phase 2 Clinical	First Affiliated Hospital Of Fujian Medical University	Alzheimer Disease	상세
SHR-1707	SHR-1707	Phase 2 Clinical		Alzheimer Disease	상세
[18F]THK-5117	[18F]THK-5117	Phase 2 Clinical	Tohoku University	Alzheimer Disease	상세
AD-35	AD-35	Phase 2 Clinical	Zhejiang Hisun Pharmaceutical Co Ltd	Alzheimer Disease	상세
Trontinemab	RO-7126209; RG-6102	Phase 2 Clinical	F. Hoffmann-La Roche Ltd	Alzheimer Disease	상세
APH-1105	APH-1105	Phase 2 Clinical	Aphios	Dementia; Alzheimer Disease	상세
RIV-1061-IR	RIV-1061; RIV-1061-IR	Phase 1 Clinical	Revivo Therapeutics	Alzheimer Disease; Cognition Disorders	상세
A ß antibody Fab		Phase 1 Clinical	Eli Lilly And Company	Alzheimer Disease	상세
RQ-9	AAT-009; RQ-9; RQ-00000009	Phase 1 Clinical	Pfizer Inc	Dementia	상세
MDR-1339	DBT-1339; MDR-1339	Phase 1 Clinical	Medifron	Alzheimer Disease	상세
AV-1959D	AV 1959D; AV-1959D	Phase 1 Clinical	Institute For Molecular Medicine, University Of California, Flinders University	Alzheimer Disease	상세
ALZ-101	ALZ-101	Phase 1 Clinical	Alzinova AB	Alzheimer Disease; Dementia	상세
PRX-012	PRX-012	Phase 1 Clinical	Prothena	Alzheimer Disease	상세
PMN-310	huPMN-310; PMN-310	Phase 1 Clinical	ProMIS Neurosciences Inc	Alzheimer Disease; Amyotrophic Lateral Sclerosis; Multiple System Atrophy	상세
CM-383	CM383; CM-383	Phase 1 Clinical	Keymed Biosciences Co Ltd	Cognitive Dysfunction; Alzheimer Disease	상세
RP-902	RP902; RP-902	Phase 1 Clinical	Risen (Suzhou) Pharma Tech Co Ltd	Alzheimer Disease	상세
ACU-193	ACU-193; ACU193	Phase 1 Clinical	Acumen Pharmaceuticals Inc	Alzheimer Disease	상세
OAB-14	OAB-14	Phase 1 Clinical	Shenyang Pharmaceutical University	Alzheimer Disease	상세
ALN-APP		Phase 1 Clinical	Sirna Therapeutics Inc	Cerebral Amyloid Angiopathy; Spinocerebellar Degenerations; Alzheimer Disease; Neurodegenerative Diseases	상세
BEY-2153	BEY-2153	Phase 1 Clinical	Beyondbio Inc	Alzheimer Disease	상세
Abeta42 antibody (Lilly)		Phase 1 Clinical	Eli Lilly And Company	Alzheimer Disease	상세
Anatabine citrate	RCP-006	Clinical	Rock Creek, Roskamp Institute	Thyroiditis, Autoimmune; Smoking Cessation; Tobacco Use Disorder; Alzheimer Disease; Inflammation	상세
123I-ABC-577	123I-ABC-577	Clinical	Nihon Medi-Physics Co Ltd	Diagnostic agents	상세
Tarenflurbil spraygel (MIKA Pharma)		Clinical	Galen Ltd, Mika Pharma Gmbh	Pain; Arthritis, Rheumatoid; Skin Diseases; Inflammation; Dermatitis, Atopic	상세
Procaine Hydrochloride/Vitamin B6/Inositol					상세
Inositol/Vitamin B1/Vitamin B2					상세

시판 약물 정보

영어 이름	연구 코드	연구 개발 단계	회사	가장 빠른 브랜드 이름	가장 빠른 승인 국가	가장 빠른 적응증	가장 빠른 승인 회사	가장 빠른 승인 날짜	적응증	임상 시험
Donanemab	LY-3002813-IV; LY-3002813-SC; LY-3002813	Approved	Eli Lilly And Company	Kisunla	United States	Alzheimer Disease	Eli Lilly And Company	2024-07-02	Neurocognitive Disorders; Brain Diseases; Dementia; Tauopathies; Alzheimer Disease; Cognitive Dysfunction; Nervous System Diseases; Central Nervous System Diseases; Neurodegenerative Diseases; Mental Disorders; Cognition Disorders	상세
Sodium Oligomannurarate	GV-971; 971	Approved	Ocean University Of China, Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences	九期一	Mainland China	Alzheimer Disease	Shanghai Greenvalley Pharmaceutical Co Ltd	2019-11-02	Parkinson Disease; Cognitive Dysfunction; Alzheimer Disease	상세
Flutemetamol (18F)	AH-110690; GE-067; 18F-GE067	Approved	Ge Healthcare	Vizamyl	United States	Contrast agents	Ge Healthcare	2013-10-25	Atherosclerosis; Cardiomyopathies; Contrast agents; Breast Neoplasms; Cognitive Dysfunction; Alzheimer Disease; Dementia; Diagnostic agents; Hydrocephalus, Normal Pressure; Cognition Disorders	상세
Inositol	4L6452S749	Approved		Nicosit					Anovulation; Depression; Anxiety; Diabetic Neuropathies; Insulin Resistance; Polycystic Ovary Syndrome; Glucose Intolerance; Infant, Newborn, Diseases; Bronchopulmonary Dysplasia; Metabolic Diseases; Lung Neoplasms; Retinopathy of Prematurity; Precancerous Conditions; Premature Birth; Hyperandrogenism; Carcinoma, Non-Small-Cell Lung	상세
Immune globulin 10% (Grifols)	KIg-10; TAL-05-0002	Approved	Bayer AG	Gamunex, Gammaked	United States	Purpura, Thrombocytopenic, Idiopathic; Immunologic Deficiency Syndromes; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	null	2003-08-27	Postural Orthostatic Tachycardia Syndrome; Kidney Failure, Chronic; Immunologic Deficiency Syndromes; Corneal Neovascularization; Common Variable Immunodeficiency; Muscular Diseases; Neuralgia; Reflex Sympathetic Dystrophy; Obsessive-Compulsive Disorder; Severe Combined Immunodeficiency; Primary Immunodeficiency Diseases; Autoimmune Diseases; Anxiety Disorders; Coronavirus Disease 2019 (COVID-19); Agammaglobulinemia; Wiskott-Aldrich Syndrome; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Purpura, Thrombocytopenic, Idiopathic; Tibial Fractures; Myasthenia Gravis	상세
Florapronol (18F)	18F-FC-119S; 18F-FC-119(S)	Approved	Korea Institute Of Radiological And Medical Sciences, Futurechem	Alzavue					Alzheimer Disease	상세
Aducanumab	BIIB-037; NI-10; BART	Approved	Neurimmune Ag	ADUHELM	United States	Alzheimer Disease	Biogen Inc	2021-06-07	Cognitive Dysfunction; Dementia; Alzheimer Disease	상세
L-Lysine hydrochloride/Cyanocobalamin/Inositol		Approved		兴邦					Malnutrition	상세
Immune Globulin Subcutaneous (Human) (Octapharma)		Approved	Octapharma	Cutaquig, Octanorm, Gammanorm	United States	Immunologic Deficiency Syndromes	null	2018-08-02	Primary Immunodeficiency Diseases; Dermatomyositis; Immunologic Deficiency Syndromes	상세
Florbetaben (18F)	MNI-815; AV-1; ZK-6013443; BAY-949172; 18F-AV-1; 18F-AV1/ZK; AV-1/ZK; BAY 94-9172; UNII-TLA7312TOI	Approved	Piramal	Neuraceq, 欧韦宁	EU	Alzheimer Disease	Life Radiopharma Berlin Gmbh	2014-02-20	Supranuclear Palsy, Progressive; Down Syndrome; Hyponatremia; Immunoglobulin Light-chain Amyloidosis; Contrast agents; Amyloidosis; Alzheimer Disease; Dementia	상세
Lecanemab	BAN-2401	Approved	Bioarctic Neuroscience	Leqembi, LEQEMBI, 乐意保	United States	Alzheimer Disease	Eisai Inc	2023-01-06	Alzheimer Disease; Dementia; Cognitive Dysfunction	상세
Florbetapir(18F)	MNI-798; AV-45	Approved	Eli Lilly And Company	Amyvid	United States	Spasms, Infantile; Rheumatic Diseases; Respiration Disorders; Multiple Sclerosis; Eye Diseases; Collagen Diseases; Skin Diseases; Hypersensitivity	Avid Radiopharmaceuticals Inc	2012-04-06	Amyloidosis; Hypersensitivity; Frontotemporal Dementia; Neurodegenerative Diseases; Collagen Diseases; Eye Diseases; Lewy Body Disease; Diagnostic agents; Parkinson Disease; Respiration Disorders; Alzheimer Disease; Rheumatic Diseases; Cognitive Dysfunction; Contrast agents; Spasms, Infantile; Skin Diseases; Multiple Sclerosis; Glioblastoma	상세