4-1BB Ligand

4-1BB Ligand 분자 정보

영어 이름Tumor necrosis factor ligand superfamily member 9시판 약물 수0
임상 약물 수2표적 별명4-1BB ligand,4-1BBL
최고 연구 개발 단계Phase 2 Clinical
영어 이름Tumor necrosis factor ligand superfamily member 9
표적 별명4-1BB ligand,4-1BBL
시판 약물 수0
임상 약물 수2
최고 연구 개발 단계Phase 2 Clinical

4-1BB Ligand분자 배경

Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.

4-1BB Ligand분자 별명

4-1BB Ligand,TNFSF9,CD137L

임상 약물 정보

영어 이름연구 코드연구 개발 단계회사적응증임상 시험
RTX-224RTX-224Phase 2 ClinicalRubius Therapeutics IncCarcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Skin Melanoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms
상세
RP-3RP-3Phase 2 ClinicalReplimune IncBiliary Tract Neoplasms; Carcinoma, Hepatocellular; Colorectal Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck
상세

제품 리뷰

  • P***l2025-05-30
    3사람들이 좋아합니다
    Hi, I work for a start-up company, Nkure Therapeutics, in Bangalore. We have used GMP-4-1BBL from AcroBio and it worked well in our hands for a therapeutic dose. We culture primary cells as such NK cells to provide a cell therapy against cancer. We are happy with the service and the product quality as well. We compared the data of NK cell expansion with Croyez 4-1-BBL and AcroBio 4-1-BBL and realized there is no difference in the potency, however there is a huge difference in the price. AcroBio provides smaller pack size with a good price range as well.
  • a***n2025-02-06
    3사람들이 좋아합니다
    Your FACS antibodies of great. worked greatly to study immune cell and activation markers study with extradentary available conjugates for Flow cytometry
  • 분자 정보
  • 제품 목록
  • 제품 리뷰
  • 임상 약물 정보
문의하기

전화
글로벌: +1 800-810-0816 (무료)
아시아태평양: +86 400-682-2521

주소 서울특별시 송파구 법원로11길 11, 제3층 제비-314,315호