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Your Position: > Protein > Reg4 > RE4-H5221

Human Reg4 Protein, His Tag

  • Synonym
    REG4,GISP,REG-IV,RELP
  • Source
    Human Reg4, His Tag(RE4-H5221) is expressed from human 293 cells (HEK293). It contains AA Asp 23 - Pro 158 (Accession # AAH17089).
    Predicted N-terminus: Asp 23
  • Molecular Characterization
    Reg4 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 16.7 kDa. The protein migrates as 18 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Reg4 SDS-PAGE

Human Reg4, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Regenerating islet-derived protein 4 (REG4) is also known as Gastrointestinal secretory protein (GISP), REG-like protein (RELP). REG4 contains one C-type lectin domain. REG4 has calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. REG4 may be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.
  • Clinical and Translational Updates

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Datasheet & Documentation

DMF 신청
DMF (Drug Master File)

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