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Your Position: > Aneuro > LRRK2 > LK2-H5245

Human LRRK2 (G2019S) Protein, His Tag

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  • Synonym
    PARK8,Leu-rich repeat/LRR-containing protein kinase 2,Dardarin
  • Source
    Human LRRK2 (G2019S), His Tag (LK2-H5245) is expressed from human 293 cells (HEK293). It contains AA Met 968 - Gln 2527 (Accession # Q5S007(G2019S)).
    Predicted N-terminus: His
  • Molecular Characterization
    Online-Res(Met 968 - Gln 2527) Q5S007 (G2019S)

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 179.5 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Shipping
    This product is supplied and shipped as sterile liquid solution with dry ice, please inquire the shipping cost.
  • Background
    Leucine-rich repeat kinase 2 (LRRK2), also known as dardarin and PARK8, is a kinase enzyme that in humans is encoded by the LRRK2 gene. LRRK2 is a member of the leucine-rich repeat kinase family, which phosphorylates a broad range of proteins involved in multiple processes such as neuronal plasticity, autophagy, and vesicle trafficking. Mutations in the LRRK2 gene causes one of the most common monogenic forms of Parkinson disease (PD) . Also, several polymorphic variants in LRRK2 also modulate risk of sporadic PD.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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가격(KRW) : 660,000

가격(KRW) : 5,940,000

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  • Latest Research Phase:Phase 3 Clinical

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