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Your Position: > TME Relevant Pathway > Her2 > HE2-H5212

Human Her2 / ErbB2 Protein, Tag Free

  • 동의어
    ERBB2,CD340,HER-2/neu,HER2,MLN19,NEU,NGL,TKR1
  • 출처
    Human Her2, Tag Free (HE2-H5212) is expressed from human 293 cells (HEK293). It contains AA Thr 23 - Thr 652 (Accession # P04626-1).
    Predicted N-terminus: Thr 23
  • 분자 표징
    Online(Thr 23 - Thr 652) P04626-1

    This protein carries no "tag".

    The protein has a calculated MW of 70.1 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • 내독소
    Less than 1.0 EU per μg by the LAL method.
  • 순도

    >95% as determined by SDS-PAGE.

  • 레시피

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • 재구성

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 보관

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;

    2. -70°C for 3 months under sterile conditions after reconstitution.

SDS-PAGE
Human Her2, Tag Free (Cat. No. HE2-H5212) SDS-PAGE gel

Human Her2, Tag Free on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
Human Her2, Tag FreeHuman Her2, Tag Free (Cat. No. HE2-H5212) ELISA bioactivity

Immobilized Human Her2, Tag Free (Cat. No. HE2-H5212) at 1 μg/mL (100 μL/well)can bind Trastuzumab with a linear range of 0.2-2 ng/mL (QC tested).

Bioactivity-BLI
Human_FcRn_Heterodimer_Protein_Bli

Loaded Hercecptin on AHC Biosensor, can bind Human Her2, Tag Free (Cat. No. HE2-H5212) with an affinity constant of 1.45 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).

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ETD of in-stock products: 4 business days

가격(KRW) : 480,000

가격(KRW) : 1,980,000

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약물 개발 현황

  • Number of Launched Drugs:30 Details
  • Number of Drugs in Clinical Trials:165 Details
  • Latest Research Phase:Approved

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