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Laminin 511 E8

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LA8-H5283 Human Human Laminin 511 E8 Protein, Fc Tag
LA8-H5283-sds

일부의 생물활성 데이터

LA8-H5283-MALS-HPLC
Human Laminin 511 E8, Fc TagHuman Laminin 511 E8, Fc Tag (Cat. No. LA8-H5283) ELISA bioactivity

Immobilized Human ITGA6&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52W7) at 5 μg/mL (100 μL/well) can bind Human Laminin 511 E8, Fc Tag (Cat. No. LA8-H5283) with a linear range of 0.1-4 ng/mL (QC tested).

사용자 리뷰

Synonym Name

Laminin 511 E8, LN-511-E8, Laminin-511 E8

Background

Laminin 511 E8 is a truncated laminin 511, which is one of the ECM proteins. laminin E8s serve as functionally minimal forms that retain the full capability for binding to integrins. Laminin 511-E8 consists of the C-terminal end of the alpha 5, beta 1, and gamma 1 chains. The laminin-511 heterotrimer (α5β1γ1) is one of the isoforms to be identified and a potent adhesive and pro-migratory substrate for a variety of normal and tumor cell lines in vitro. Previous studies indicated that laminin-511 contributes to tumor dissemination and metastasis in advanced breast carcinomas and other tumor types. Additionally, latest research uncovered that Laminin 511 might be a target antigen and involved in autoimmune pancreatitis.

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